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ProteomicsA new family of ribosome hibernation factors in ArchaeaA new family of ribosome hibernation factors in Archaea
Ribosome hibernation preserves translation machinery during stress, yet its mechanisms in Archaea remain poorly defined. Here, we identify HibA, a previously unrecognized family of hibernation factors widespread in Archaea. HibA consists of a bacterial-like HPF/RaiA domain fused to a Cystathionine B...
ORGANISM(S): Pyrococcus abyssi GE5 
2026-03-24 | PXD073243 | Pride
Archaea Ribosome Hibernation 
ProteomicsCryo-EM Structures of 30S:mRNA Complexes in Saccharolobus solfataricus: Unveiling Archaeal Features and Eukaryotic Proximity
The archaeal ribosome is of the eukaryotic type. Genomic and phylogenetic studies have indicated that TACK and Asgard, the closest relatives of eukaryotes, have ribosomes containing eukaryotic ribosomal proteins not found in other archaeal branches, eS25, eS26 and eS30. In our study, we investigated...
ORGANISM(S): Sulfolobus solfataricus 
2025-05-07 | PXD053103 | Pride
Es26 Es25 Translation initiation Es30 Leaderless mrna 
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