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TranscriptomicsComparative transcriptome analysis of Saccharomyces cerevisiae wild type and M-NM-^Tasc1 strain
Asc1p and its essential orthologues in higher eukaryotes, as e.g. RACK1 in mammals, are involved in several distinct cellular signaling processes, but the implications of a total deletion have never been assessed in a comprehensive genome-wide manner. This study reveals the major cellular processes ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-30 | E-GEOD-34286 | biostudies-arrayexpress
TranscriptomicsNew target genes of MITF-induced microRNA-211 contribute to melanoma cell invasion
IGR39 cells, seeded at a density of 6x104 cells/well in 12-well culture plates, were transfected with 5 nM of miR-211 mimic or negative control (NCM) as described in the main text. Samples for total RNA extraction were collected 48h after transfection. RNA quality was assessed using RNA 6000 NanoChi...
ORGANISM(S): Homo sapiens 
2013-08-01 | E-MEXP-3749 | biostudies-arrayexpress
TranscriptomicsSex-specific effects of prenatal stress in 5-Htt deficient mice: towards molecular mechanisms of gene x environment interactions
prenatal stress response, genetic modification Background: Prenatal stress (PS) exposure has been shown to increase the risk for emotional disorders in later life. Furthermore, the serotonin transporter (5-HTT) genotype is suggested to exert a modulating effect on the association between early life ...
ORGANISM(S): Mus musculus 
2011-12-12 | E-GEOD-26025 | biostudies-arrayexpress
MetabolomicsA homeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism

Cellular senescence affects many physiological and pathological processes and is characterized by durable cell cycle arrest, an inflammatory secretory phenotype and metabolic reprogramming. Here, by using dynamic transcriptome and metabolome profiling in human fibroblasts with different subtypes ...

2024-01-09 | MTBLS7118 | MetaboLights
UnknownInterplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.
Not available
S-EPMC3217025 | biostudies-literature
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