Schmitz K K - OmicsDI

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Unknown (940)
Transcriptomics (31)
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Homo sapiens (29)
Mus musculus (19)
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Arabidopsis thaliana (2)
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Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S (1)

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biostudies-arrayexpress (35)
pride (25)
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Mass Spectrometry (25)
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Instrument Platform

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Axon GenePix 4000B scanning hardware (3)
Direct infusion MS - positive (3)
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Illumina Genome Analyzer II (1)
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QTRAP 6500 (Applied Biosystems) (1)

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ENSEMBL ID

ENSG00000151468 (1)

CHEBI ID

CHEBI:64561 (6)
CHEBI:64563 (6)
CHEBI:64549 (5)
CHEBI:64560 (5)
CHEBI:84659 (5)
CHEBI:84661 (5)
CHEBI:84662 (5)
CHEBI:84665 (5)
CHEBI:134451 (4)
CHEBI:136234 (4)
CHEBI:136256 (4)
CHEBI:136257 (4)
CHEBI:141588 (4)
CHEBI:155834 (4)
CHEBI:155835 (4)
CHEBI:3663 (4)
CHEBI:64424 (4)
CHEBI:64433 (4)
CHEBI:64483 (4)
CHEBI:64516 (4)
CHEBI:64517 (4)
CHEBI:64523 (4)
CHEBI:64566 (4)
CHEBI:66849 (4)
CHEBI:66850 (4)
CHEBI:66855 (4)
CHEBI:66857 (4)
CHEBI:66858 (4)
CHEBI:67054 (4)
CHEBI:33699 (1)

Metabolite Name

Glucose (3)
Citrate (2)
Glutamine (2)
Linoleic acid (2)
PC(16:0/0:0) (2)
PC(18:2/18:2) (2)
Phenylalanine (2)
Tyrosine (2)
Valine (2)
(+-)-Dalbergioidin (1)
(1->3)-beta-D-Galactopyranans (1)
(2,6-beta-D-Fructosyl)n (1)
1,3-beta-D-Oligoglucan (1)
1,4-beta-D-Glucan (1)
1,6-beta-D-Glucan (1)
1-16:0-lysoPE (1)
1-O-Hexadecyl-lyso-sn-glycero-3-phosphocholine (1)
1-O-feruloyl-beta-D-glucose (1)
1-kestotriose (1)
10,16-Dihydroxyhexadecanoic acid (1)
12-hydroxyjasmonic acid 12-O-beta-D-glucoside (1)
1F-beta-D-Fructosylsucrose (1)
2'-Hydroxygenistein (1)
2,6,7,4'-Tetrahydroxyisoflavanone (1)
2-Carboxy-D-arabinitol (1)
2-Hydroxy-2,3-dihydrogenistein (1)
2-Hydroxymyristic acid (1)
2-O-Methylswertianin (1)
2-Oxoglutaric Acid (1)
26-Desglucoavenacoside A (1)

IsPrivate

False (1)

Modelling Approach

Ordinary differential equation model (1)

Study type

Transcription profiling by array (21)
ChIP-chip by array (5)
ChIP-seq (3)
ChIP-chip by tiling array (2)
RNA-seq of coding RNA from single cells (1)
Methylation profiling by high throughput sequencing (1)
RNA-seq of coding RNA (1)
RNA-seq of non coding RNA (1)

Release Date

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2023 (105)
2025 (100)
2024 (96)
2021 (89)
2020 (72)
2019 (53)
2018 (48)
2016 (45)
2015 (41)
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2009 (7)
2008 (7)
2006 (7)
2004 (4)
2003 (4)
1999 (4)
2007 (3)
2005 (2)
2002 (2)
2001 (2)
2000 (1)
1998 (1)

Lab affiliation

Department Medical Biochemistry, University of Gothenburg, Gothenburg, Sweden (1)
Department of Medicine II Haematology/Oncology Goethe University Theodor-Stern-Kai 7 60590 Frankfurt Germany (1)
Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 (1)
Diabetes and Obesity Program, Garvan Institute of Medical Research, Australia (1)
Division of Neonatology, Department of Pediatrics, University of Miami Miller School of Medicine and Holtz Children's Hospital, Jackson Health System, Miami, FL, USA (1)
Drug Discovery Moffitt Cancer Center Tampa, FL, USA (1)
Farnusch Kaschani, Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany (1)
Fernando Garcia Martinez Ph.D. Proteomics & MS Specialist Proteomics Unit, Spanish National Cancer Research Centre (CNIO) Melchor Fernández Almagro 3. E28029 MADRID, SPAIN. Phone +34 912246900 ext 3112 (1)
Freie Universität Berlin, Institute of Veterinary Pathology, Faculty of Veterinary Medicine, Berlin, Germany (1)
German Cancer Reseach Center (DKFZ) (1)
Helmholtz-Centre for Environmental Research – UFZ (1)
Institut für Experimentelle Medizin (IEM) Arbeitsgruppe Systematische Proteomforschung Christian-Albrechts-Universität zu Kiel (1)
Institute for Medical Microbiology Universitätsklinikum der RWTH Aachen, Germany (1)
Institute of Biochemistry II University Hospital Building 75 Theodor-Stern-Kai 7 60590 Frankfurt (Main) (1)
Institute of Biochemistry II • Goethe University Medical School University Hospital Building 75 • Theodor-Stern-Kai 7 • 60590 Frankfurt, Germany (1)
Institute of Biochemistry II, Goethe University, Medical School, Frankfurt, Germany (1)
Institute of Clinical Pharmacology, Goethe-University, Frankfurt am Main, Germany (1)
Institute of Functional Genomics, Universtiy of Regensburg, Germany (1)
Institute of Molecular Medicine I, Medical Faculty, Heinrich Heine University Düsseldorf (1)
Institute of Molecular Medicine I, Medical Faculty, Heinrich Heine University Düsseldorf, Germany (1)
Laboratory of Cancer Signaling, University of Liège, C.H.U. Sart Tilman, Liège 4000, Belgium (1)
National Heart and Lung Institute, Faculty of Medicine, Imperial College London, UK (1)
Rudolf Virchow Zentrum – University of Würzburg (1)
Thayer School of Engineering, Dartmouth College; Hanover, NH 03755, USA Department of Convergence Medicine, Korea University College of Medicine, Seoul, Republic of Korea Vaccine Innovation Center, Korea University College of Medicine, Seoul, Republic of Korea (1)
UNIVERSITY OF GIESSEN (1)

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Discovery and design of molecular glue enhancers of CDK12-DDB1 interactions for targeted degradation of cyclin K

The CDK12 inhibitor, SR-4835, promotes the proteasomal degradation of cyclin K, contingent on the presence of CDK12 and the CUL4-RBX1-DDB1 E3 ligase complex. The inhibitor displays molecular glue activity, which correlates with its enhanced ability to inhibit cell growth. This effect is achieved by...

ORGANISM(S): Homo sapiens (Human)

2025-05-07 | PXD053505 | Pride

Paternal Depression in the Child's First Year of Life and Subsequent Father-Child Co-Residence.

Not available

S-EPMC12927712 | biostudies-literature

Discovery and design of molecular glue enhancers of CDK12-DDB1 interactions for targeted degradation of cyclin K.

Not available

S-EPMC11494886 | biostudies-literature

The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k.

Not available

S-EPMC3038675 | biostudies-literature

The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation.

Not available

S-EPMC10767194 | biostudies-literature

Jarid1b targets genes regulating development and is involved in neural differentiation [ChIP-seq]

We analyzed the genome-wide binding profile of Jarid1b in mouse ESCs. We find that Jarid1b localizes mainly to transcription start sites, of which more than 50% are also bound by Polycomb proteins and are enriched for genes encoding developmental regulators. Furthermore, we generated genome-wide map...

ORGANISM(S): Mus musculus

2011-10-26 | E-GEOD-31966 | biostudies-arrayexpress

Jarid1b targets genes regulating development and is involved in neural differentiation

This SuperSeries is composed of the following subset Series: GSE31966: Jarid1b targets genes regulating development and is involved in neural differentiation [ChIP-seq] GSE31967: Jarid1b targets genes regulating development and is involved in neural differentiation [expression array] Refer to indivi...

ORGANISM(S): Mus musculus

2011-10-26 | E-GEOD-31968 | biostudies-arrayexpress

Lysiphyllum strychnifolium (Craib) A. Schmitz Extracts Moderate the Expression of Drug-Metabolizing Enzymes: In Vivo Study to Clinical Propose.

Not available

S-EPMC9961159 | biostudies-literature

Antidiabetic potential of Lysiphyllum strychnifolium (Craib) A. Schmitz compounds in human intestinal epithelial Caco-2 cells and molecular docking-based approaches.

Not available

S-EPMC9442914 | biostudies-literature

Comprehensive systems biology analysis of a seven-month cigarette smoke inhalation study in C57BL/6 mice

Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of smoke derived from a prototype modified risk tobacco product (pMRTP) as compare...

2015-11-19 | MTBLS143 | MetaboLights

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