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UnknownKinetics of oxytocin effects on amygdala and striatal reactivity vary between women and men.
Not available
S-EPMC7235226 | biostudies-literature
ProteomicsFecal metaproteomics reveals reduced gut inflammation and changed microbial metabolism following lifestyle-induced weight loss
Aims Gut microbiota-mediated inflammation promotes obesity-associated low-grade inflammation, which represents a hallmark of the metabolic syndrome (MetS). Lifestyle-induced weight loss (WL) is regarded as an efficient therapy to reverse MetS and to prevent disease progression. The objective of this...
ORGANISM(S): human gut metagenome 
2021-04-19 | PXD020902 | Pride
Metaproteomics Obesity Metabolic syndrome Microbiome Gut inflammation Weight loss 
TranscriptomicsIdentification of a potent and selective chemical probe for exploring the role of Mediator complex-associated protein kinases CDK8 and CDK19 in human disease [beta-catenin organoids]
There is an unmet need for chemical tools to explore the role of the Mediator complex in human pathologies ranging from cancer to cardiovascular disease. Here we determine that CCT251545 a WNT-pathway inhibitor discovered by cell-based screening is a potent and selective chemical probe for the Medi...
ORGANISM(S): Mus musculus 
2015-10-26 | E-GEOD-67847 | biostudies-arrayexpress
TranscriptomicsIdentification of a potent and selective chemical probe for exploring the role of Mediator complex-associated protein kinases CDK8 and CDK19 in human disease [LS-174-T]
There is an unmet need for chemical tools to explore the role of the Mediator complex in human pathologies ranging from cancer to cardiovascular disease. Here we determine that CCT251545 a WNT-pathway inhibitor discovered by cell-based screening is a potent and selective chemical probe for the Medi...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-67846 | biostudies-arrayexpress
TranscriptomicsIdentification of a potent and selective chemical probe for exploring the role of Mediator complex-associated protein kinases CDK8 and CDK19 in human disease [Colo205]
There is an unmet need for chemical tools to explore the role of the Mediator complex in human pathologies ranging from cancer to cardiovascular disease. Here we determine that CCT251545 a WNT-pathway inhibitor discovered by cell-based screening is a potent and selective chemical probe for the Medi...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-67845 | biostudies-arrayexpress
TranscriptomicsH3K64me3 and H3K9me3 profiling at promoters in mouse embryonic stem cells
Histone modifications are central to the regulation of all DNA-dependent processes but the repertoire of known modifications is far from complete. Lysine 64 of Histone H3 (H3K64) lies within the globular domain of H3 at a structurally important position within the nucleosome. We identify tri-methyla...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-16185 | biostudies-arrayexpress
UnknownAssociations of post-traumatic stress disorder and depression with cognitive performance over the first year following Glasgow Coma Scale 13-15 traumatic brain injury: a TRACK-TBI Study.
Not available
S-EPMC12716588 | biostudies-literature
Genomicsena-DATASET-IJC-07-11-2014-17:58:39:549-794 - samples
Cancer exome reads consisting of FASTQ paired end reads from bone marrow samples
EGAD00001001058 | EGA
GenomicsMDS Sequencing Project Cancer Cell
Myelodysplastic syndromes (MDS) are uncommon entities, heterogeneous clinically and cytogenetically. The aim of the present study is to determine genetic alteration in this subset of patients. Expected results: Identification of new aberrations and genetic markers in order to detect novel genes invo...
EGAS00001001011 | EGA
GenomicsIJC Myelodysplastic Syndromes Sequencing Group
Data Access Committee EGAC00001000257
EGAC00001000257 | EGA
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