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TranscriptomicsGene expression profile of cell lines 2106T, H1975 and MeWo after knockdown of PAEP.
Gene expression profile was analyzed after knockdown of PAEP in lung cancer cell lines 2106T and H1975 as well as in skin cancer cell line MeWo. The aim of the study was to investigate the role of PAEP and its protein product glycodelin in lung cancer cell lines. Cells were treated with a control si...
ORGANISM(S): Homo sapiens 
2015-04-22 | E-GEOD-60888 | biostudies-arrayexpress
MetabolomicsSpecific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata
The native diploid tobacco Nicotiana attenuata produces abundant, potent anti-herbivore defense metabolites known as 17-hydroxygeranyllinalool diterpene glycosides (HGL-DTGs) whose glycosylation and malonylation biosynthetic steps are regulated by jasmonate signaling. To characterize the biosyntheti...
2021-10-06 | MTBLS1819 | MetaboLights
UnknownSubtle Role for Adenylate Kinase 1 in Maintaining Normal Basal Contractile Function and Metabolism in the Murine Heart.
Not available
S-EPMC8044416 | biostudies-literature
UnknownOver-expression of mitochondrial creatine kinase in the murine heart improves functional recovery and protects against injury following ischaemia-reperfusion.
Not available
S-EPMC5909653 | biostudies-literature
TranscriptomicsMethylation profiling of the human CNTNAP2 gene in brain using high-resolution tiling arrays.
Accelerated brain development is a unique feature of the human species. Not only the size but also morphology, in particular the connections between frontal cortex and basal ganglia distinguish the human brain from great apes and other primates. Recent findings suggest that structural features which...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-52948 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of the chimpanzee CNTNAP2 gene in brain using high-resolution tiling arrays.
Accelerated brain development is a unique feature of the human species. Not only the size but also morphology, in particular the connections between frontal cortex and basal ganglia distinguish the human brain from great apes and other primates. Recent findings suggest that structural features which...
ORGANISM(S): Pan troglodytes 
2014-02-20 | E-GEOD-52949 | biostudies-arrayexpress
UnknownHeart failure hospitalizations and clinical outcomes in patients undergoing tricuspid transcatheter edge-to-edge repair: Insights from EuroTR.
Not available
S-EPMC12482852 | biostudies-literature
TranscriptomicsEcdysone signaling and transcript signature in Drosophila cells resistant against methoxyfenozide
Methoxyfenozide (RH-2485) represents the group of non-steroidal ecdysteroid agonists with a dibenzoylhydrazine structure, that are used as novel biorational insecticides in the control of insect pests. Here we report on the selection of Drosophila melanogaster S2 cells for resistance to inhibition o...
ORGANISM(S): Drosophila melanogaster 
2010-11-08 | E-GEOD-17748 | biostudies-arrayexpress
TranscriptomicsGRHL1 acts as a tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3
Neuroblastoma is an embryonic solid tumor of neural crest origin and accounts for 11% of all cancer-related deaths in children. Novel therapeutic strategies are therefore urgently required. MYCN oncogene amplification, which occurs in 20% of neuroblastomas, is a hallmark of high risk. Here we aimed ...
ORGANISM(S): Homo sapiens 
2014-05-22 | E-GEOD-47407 | biostudies-arrayexpress
TranscriptomicsCDH1 knockout in mice
Employing Cre/loxP technology, a mouse model of liver specific Cdh1 (E-cadherin) depletion was created (fl/fl | +/wt). Previously, the mice had already been compared to littermates with normal Ecadherin levels (fl/fl | wt/wt), using a broad range of laboratory methods (Serum parameters, long-term we...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-54234 | biostudies-arrayexpress
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