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TranscriptomicsHepatocellular carcinomas (HCC) in mice transduced in utero with feline immunodeficiency virus-based vectors (expression)
Fetal mice (16 days gestation) were administered feline immunodeficiency virus (FIV)-based lentiviral viral particles containing the gene encoding GFP. Six liver tumors developed in three mice between the ages of 273 and 484 days, each mouse developed 2 tumors. These tumors and non-tumorous liver t...
ORGANISM(S): Mus musculus 
2013-09-11 | E-GEOD-19306 | biostudies-arrayexpress
TranscriptomicsHepatocellular carcinomas (HCC) in mice transduced in utero with feline immunodeficiency virus-based vectors (CGH)
Fetal mice (16 days gestation) were administered FIV-based lentiviral viral particles containing the gene encoding EGFP. Six liver tumors developed in three mice (1 male, 2 females) between the ages of 273 and 484 days, each mouse developed 2 tumors. These tumors and non-tumorous liver tissue from ...
ORGANISM(S): Mus musculus 
2013-09-11 | E-GEOD-25900 | biostudies-arrayexpress
TranscriptomicsChronic liver inflammation-induced double strand DNA breaks enhance hepatocarcinogenesis
Surgical resection is the preferred treatment for Hepatocellular carcinoma; however, it induces tumor recurrence. Our objective was to understand the molecular mechanisms linking liver regeneration under chronic-inflammation to tumorigenesis. Mdr2-knockout mice, a model of inflammation-associated ca...
ORGANISM(S): Mus musculus 
2010-01-03 | E-GEOD-14539 | biostudies-arrayexpress
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