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MetabolomicsOxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers
Resistance to endocrine treatments and CDK4/6 inhibitors is considered a near-inevitability in most patients with estrogen receptor positive breast cancers (ER + BC). By genomic and metabolomics analyses of patients' tumours, metastasis-derived patient-derived xenografts (PDX) and isogenic cell line...
2023-06-27 | MTBLS3342 | MetaboLights
UnknownThe Schnitzler syndrome.
Not available
S-EPMC3018454 | biostudies-literature
GenomicsSpatial transcriptomics analysis of urticarial rash skin from patients with Schnitzler syndrome
Spatial transcriptomics analysis of urticarial rash skin from patients with Schnitzler syndrome
PRJNA1237236 | ENA
UnknownMolecular genetic investigation, clinical features, and response to treatment in 21 patients with Schnitzler syndrome.
Not available
S-EPMC5877784 | biostudies-literature
UnknownBackground and Clinical Features of a Unique and Mysterious Autoinflammatory Disease, Schnitzler Syndrome.
Not available
S-EPMC11765222 | biostudies-literature
OtherSpatial transcriptomics analysis of urticarial rash skin from patients with Schnitzler syndrome
We conducted a multicenter, open-label, single-arm phase II trial (SCan Study) to evaluate the efficacy and safety of canakinumab in 5 Japanese patients with Schnitzler syndrome (SchS), based on a similar study conducted in Germany. As part of this study, spatial transcriptomics of urticarial rash s...
ORGANISM(S): Homo sapiens 
2025-04-21 | GSE292123 | GEO
TranscriptomicsSingle-cell RNA sequencing of peripheral blood from Schnitzler syndrome patients before and after canakinumab treatment
We conducted a multicenter, open-label, single-arm phase II trial (SCan Study) to evaluate the efficacy and safety of canakinumab in 5 Japanese patients with Schnitzler syndrome (SchS), based on a similar study conducted in Germany. In this trial, single-cell RNA sequencing (scRNA-seq) of peripheral...
ORGANISM(S): Homo sapiens 
2025-04-21 | GSE292122 | GEO
GenomicsSingle-cell RNA sequencing of peripheral blood from Schnitzler syndrome patients before and after canakinumab treatment
Single-cell RNA sequencing of peripheral blood from Schnitzler syndrome patients before and after canakinumab treatment
PRJNA1237239 | ENA
UnknownRheumatic involvement and bone scan features in Schnitzler syndrome: initial and follow-up data from a single-center cohort of 25 patients.
Not available
S-EPMC7677784 | biostudies-literature
UnknownEvidence of B Cell Clonality and Investigation Into Properties of the IgM in Patients With Schnitzler Syndrome.
Not available
S-EPMC7793813 | biostudies-literature
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