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ProteomicsPhosphoproteomic analysis of control and Ste20-like kinase (Slk) knockdown cortical neurons
The Ste20-like kinase (Slk) is a serine/threonine kinase that regulates cytoskeletal organization, apoptosis, and cell polarity in non-neuronal cells. In neurons, Slk guides dendrite morphogenesis and inhibitory synapse stability, thereby controlling excitation-inhibition balance. We compared the ph...
ORGANISM(S): Mus musculus (Mouse) 
2026-10-06 | PXD072739 | Pride
Tmt Knockdown Phosphoproteomics Cortical neurons Ste20-like kinase 
TranscriptomicsTranscription profiling by array of human gangliogliomas and adjacent tissue
Gangliogliomas, the most frequent neoplasms in patients with pharmacoresistant focal epilepsies, are characterized by histological combinations of glial and dysplastic neuronal elements, a highly differentiated phenotype and rare gene mutations.

Here, we have used discrete microdissected gang...
ORGANISM(S): Homo sapiens 
2008-10-03 | E-MEXP-1690 | biostudies-arrayexpress
ProteomicsIdentification of a Ste20-like kinase-dependent network orchestrating cytoskeletal and synaptic development of cortical neurons. Untargeted phosphorylation analysis
The Ste20-like kinase (Slk) is a serine/threonine kinase that regulates cytoskeletal organization, apoptosis, and cell polarity in non-neuronal cells. In neurons, Slk guides dendrite morphogenesis and inhibitory synapse stability, controlling excitation-inhibition balance through parvalbumin interne...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-10-02 | PXD073661 | Pride
Germinal center kinases Kinase signaling Affinity purification-mass spectrometry Lc/ms Protein-protein interactions Phosphoproteomics 
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