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TranscriptomicsMechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch
Hypoxia-induced cell injury has been related to multiple pathological conditions. In order to render hypoxia-sensitive cells and tissues resistant to low O2 environment, in this current study, we used Drosophila melanogaster as a model to dissect the mechanisms underlying hypoxia-tolerance. A D. mel...
ORGANISM(S): Drosophila melanogaster 
2010-06-25 | E-GEOD-8803 | biostudies-arrayexpress
TranscriptomicsNon-coding transcription within the Igh distal VH region at PAIR elements affects the 3D structure of the Igh locus in pro-B cells
Non-coding sense and antisense germline transcription within the immunoglobulin heavy chain locus precedes V(D)J recombination and has been proposed to be associated with Igh locus accessibility, although its precise role remains elusive. However, no global analysis of germline transcription through...
ORGANISM(S): Mus musculus 
2012-10-18 | E-GEOD-40984 | biostudies-arrayexpress
TranscriptomicsGenome-wide Expression Assay Comparison Across Frozen and Fixed Postmortem Brain Tissue Samples
Comparison between in vitro transcription- and cDNA-mediated annealing, selection and ligation (DASL)-based assays on brain-specific reference RNA, and postmortem frozen and formalin fixed brain tissue from autistic and control cases. Investigation of data preprocessing techniques for DASL-assayed ...
ORGANISM(S): Homo sapiens 
2012-04-02 | E-GEOD-28475 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse brain regions (bed nucleus of the stria terminalis, hippocampus, hypothalamus, periaqueductal gray, and pituitary gland) in six mouse strains (129S6/SvEvTac, A/J, C57BL/6J, C3H/HeJ, DBA/2J, and FVB/NJ)
Gene expression patterns were determined from five brain regions (bed nucleus of the stria terminalis, hippocampus, hypothalamus, periaqueductal gray, and pituitary gland) in six mouse strains (129S6/SvEvTac, A/J, C57BL/6J, C3H/HeJ, DBA/2J, and FVB/NJ). At least two replicate samples per brain regio...
ORGANISM(S): Mus musculus 
2009-09-16 | E-GEOD-4734 | biostudies-arrayexpress
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