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GenomicsLarge-scale methylation domains mark a functional subset of neuronally expressed genes
DNA methylation is essential for embryonic and neuronal differentiation, but the function of most genomic DNA methylation marks are poorly understood. Generally the human genome is highly methylated (>70%) except for CpG islands and gene promoters. However, it was recently shown that the IMR90 human...
ORGANISM(S): Homo sapiens 
2011-06-23 | E-GEOD-25930 | biostudies-arrayexpress
MetabolomicsEvaluation of ambient mass spectrometry tools for assessing inherent postharvest pepper quality

Horticulturists are interested in evaluating how cultivar, environment, or production system inputs can affect postharvest quality. Ambient mass spectrometry approaches enable analysis of minimally processed samples under ambient conditions and offer an attractive high-throughput alternative for ...

2022-03-04 | MTBLS2587 | MetaboLights
UnknownDCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.
Not available
S-EPMC10766610 | biostudies-literature
UnknownEffects of a 12-Week Periodized Resistance Training Program on Resting Brain Activity and Cerebrovascular Function: A Nonrandomized Pilot Trial.
Not available
S-EPMC9379950 | biostudies-literature
GenomicsHigh salt reduces the activation of IL-4+IL-13 stimulated macrophages
High salt (NaCl) intake is a major risk factor for cardiovascular disease; high NaCl has also been shown to be a powerful modulator of pro-inflammatory immune cell polarization. To investigate the effect of high NaCl on the polarization of M(IL-4+IL-13) macrophages we performed gene expression analy...
ORGANISM(S): Mus musculus 
2015-02-07 | E-MTAB-3140 | biostudies-arrayexpress
UnknownInteraction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.
Not available
S-EPMC5016110 | biostudies-literature
TranscriptomicsComparison of post-mortem tissue from Brodman Brain BA22 region between schizophrenic and control patients
Transcriptional analysis of the superior temporal cortex (BA22) in schizophrenia: Pathway insight into disease pathology and drug development Schizophrenia is a highly debilitating psychiatric disorder which is known to have heritable genetic and environmental components. To gain some insight into t...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-21935 | biostudies-arrayexpress
MetabolomicsMetabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease

BACKGROUND: One-third of inflammatory bowel disease (IBD) patients show no response to infliximab (IFX) induction therapy, and approximately half of patients responding become unresponsive over time. Thus, identification of potential treatment response biomarkers are of great cl...

2022-01-13 | MTBLS239 | MetaboLights
ProteomicsDcitri - Whole organism, Normalized peptide spectral count numbers (Ramseyetal,plosone2015)
abundance based on Normalized peptide spectral count numbers, Interaction consistency score: 2.4, Coverage: 3
ORGANISM(S): 121845 
2015-00-00 | 3479534116 | PAXDB
ProteomicsDcitri - Whole organism, Normalized peptide spectral count numbers (Ramseyetal,plosone2015)
abundance based on Normalized peptide spectral count numbers, Interaction consistency score: 2.2, Coverage: 3
ORGANISM(S): 121845 
2015-00-00 | 2717572991 | PAXDB
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