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TranscriptomicsWhole lung gene expression from BXD mouse strains
Parental and BXD mouse lines were received from Jackson Laboratory and University of Tennessee Health Science Center. All animals were housed at UTHSC before sacrifice. Mice were killed by cervical dislocation and whole lungs including blood were removed and placed in RNAlater. Total RNA was extract...
ORGANISM(S): Mus musculus 
2011-12-01 | E-MTAB-848 | biostudies-arrayexpress
TranscriptomicsRegulatory T and T helper cells from BXD mouse strains
Parental and BXD mouse lines were received from Jackson Laboratory and The Oak Ridge National Laboratory. Splenocytes were isolated and stained with anti-CD4 and anti-CD25 antibodies. CD4+ T cells were separated into CD4+CD25+ Treg and CD4+CD25- Th cells. Tregs and Th cell were collected from splee...
ORGANISM(S): Mus musculus 
2011-12-15 | E-MTAB-836 | biostudies-arrayexpress
TranscriptomicsTime series of flu-infected lungs of DBA/2J and C57BL/6J mice
DBA/2J (D2) and C57BL/6J mice (B6) were infected intra-nasally with 2x10^3 FFU of influenza A H1N1 (PR8) virus. Lungs were collected from mock-infected controls or at day 1,2,3,4 post infection. Expression data were obtained from three independent experiments. We infected a highly susceptible mouse ...
ORGANISM(S): Mus musculus 
2011-12-01 | E-MTAB-835 | biostudies-arrayexpress
TranscriptomicsHigh-time-resolution dynamic analysis of human regulatory T cell (Treg) / CD4+ T-effector cell (Teff) activation
Human FOXP3+CD25+CD4+ regulatory T cells (Tregs) play a dominant role in the maintenance of immune homeostasis. Several genes are known to be important for murine Tregs, but for human Tregs the genes and underlying molecular networks controlling the suppressor function still largely remain unclear. ...
ORGANISM(S): Homo sapiens 
2012-11-23 | E-GEOD-11292 | biostudies-arrayexpress
UnknownThe mouse Pax2(1Neu) mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney.
Not available
S-EPMC19453 | biostudies-literature
TranscriptomicsRNA-seq influenza infected B6 & D2 mice
The host response to influenza A infections is strongly influenced by host genetic factors. Animal models of genetically diverse mouse strains are well suitable to identify host genes involved in severe pathology, viral replication and immune responses. Here, we have utilizing a dual RNAseq approach...
ORGANISM(S): Mus musculus 
2015-07-06 | E-GEOD-66040 | biostudies-arrayexpress
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