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ProteomicsMammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment
Fully-grown oocytes are transcriptionally silent and must stably maintain mRNAs needed for oocyte meiotic maturation and early embryonic development. However, where and how mammalian oocytes store maternal mRNAs is unclear. Here, we report that mammalian oocytes accumulate mRNAs in a mitochon...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-25 | PXD036974 | Pride
Mouse Oocytes Lc-esi-ms/ms Dda Mrna storage 
ProteomicsMammalian oocytes store proteins in cytoplasmic lattices
Oocytes must accumulate and store maternal factors such as proteins during growth to sustain the first stages of embryonic development. How mammalian oocytes store maternal proteins is not understood. Here, we show that mouse and human oocytes store proteins on cytoplasmic lattices. With super-resol...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-23 | PXD038575 | Pride
Dia Cytoplasmic lattices Oocytes Lc-ms/ms 
TranscriptomicsTranscriptome comparison of oocytes obtained from in vitro culture and in vivo
The comparison of trancriptomes was part of the study by Pfender, Kuznetsov, Pasternak et al, titled: "Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes". The goal was to check if the oocytes cultured in vitro in follicles (for RNAi studies) correspond to re...
ORGANISM(S): Mus musculus 
2015-07-06 | E-GEOD-68150 | biostudies-arrayexpress
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