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TranscriptomicsExpression data from Rad21 knock-down in ES cells
The Cohesin complex has recently been described to regulate gene expression. We wanted to determine the gene expression profile specific in mouse ES cells after depletion of the Cohesin subunit Rad21. We used microarrays to detail the global programme of gene expression underlying depletion of Rad21...
ORGANISM(S): Mus musculus 
2011-05-19 | E-GEOD-23923 | biostudies-arrayexpress
TranscriptomicsThe Cohesin Complex Cooperates with Pluripotency Transcription Factors in the Maintenance of Embryonic Stem Cell Identity
Embryonic stem cells (ESCs) cells run a self-renewal gene expression program, requiring the expression of certain transcription factors accompanied by a particular chromosome organization to maintain a balance between pluripotency and the capacity for rapid differentiation. However, how transcriptio...
ORGANISM(S): Mus musculus 
2011-05-19 | E-GEOD-24030 | biostudies-arrayexpress
MetabolomicsGlycerophospholipid remodeling is critical for orthoflavivirus infection

Flavivirus infection is tightly connected to host lipid metabolism. Here, we performed shotgun lipidomics of cells infected with neurotropic Zika, West Nile and tick-borne encephalitis viruses, as well as dengue and yellow fever virus. Early in infection specific lipids accumulated, e.g., neutral...

2025-02-24 | MTBLS11030 | MetaboLights
TranscriptomicsGene expression of resting memory, resting naive and in vitro activated memory CD8+CD127+ T cells from spleen and bone marrow (BM)
To understand differences between resting and activated memory CD8+ T cells, we compared the global gene expression of ex vivo isolated naive and spleen and BM memory cells to in vitro activated spleen and BM memory cells. Single cell suspension from the spleen and bones of aged C57BL/6 mice were pr...
ORGANISM(S): Mus musculus 
2015-02-05 | E-GEOD-62691 | biostudies-arrayexpress
GenomicsGenome-wide maps of Rad21 in R1/E embryonic stem cells and R1/E derived Embryoid bodies
ChIP-seq based determination of Rad21 binding sites in embryonic stem cells (ESC) and ESC derived Embryoid Bodies (EB) identified Examination of Rad21 binding sites in 2 cell types
ORGANISM(S): Mus musculus 
2011-05-19 | E-GEOD-24029 | biostudies-arrayexpress
GenomicsGenome-wide maps of CTCF in R1/E embryonic stem cells
ChIP-seq based determination of CTCF binding sites in embryonic stem cells (ESC) Examination of CTCF binding sites
ORGANISM(S): Mus musculus 
2011-05-19 | E-GEOD-25777 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of skeletal muscle tissue from spontaneously hypertensive rats and normotensive rats in a set of recombinant inbred strains
We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.
ORGANISM(S): Rattus norvegicus 
2008-04-15 | E-TABM-458 | biostudies-arrayexpress
UnknownModelling unveils sex differences of signalling networks in mouse embryonic stem cells
Not available
S-SCDT-10_15252-MSB_202211510 | biostudies-other
TranscriptomicsTranscription profiling by array of rat liver from recombinant inbred strains derived from BN and SHR rats
We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.
ORGANISM(S): Rattus norvegicus 
2011-07-12 | E-MTAB-323 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of rat aorta from recombinant inbred strains derived from BN and SHR rats
We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.
ORGANISM(S): Rattus norvegicus 
2011-07-12 | E-MTAB-322 | biostudies-arrayexpress
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