Sort   by:  
 Page size 
GenomicsEvolutionary comparison of CTCF and YY1 binding in primate lymphoblastoid cell lines
We performed an evolutionary comparison of the binding of the TF CTCF in human, chimpanzee, gorilla, orang-utan, macaque, baboon and marmoset using lymphoblastoid cell lines (LCLs). We also probes YY1 binding in human, chimpanzee, orang-utan and baboon LCLs as well as human and mouse liver.
ORGANISM(S): Pan troglodytes 
2013-11-20 | E-MTAB-1511 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of human PBMCs and tumor-infiltrated lymphocytes from melanoma patients analysed prior to checkpoint inhibitor treatment
We performed single-cell RNA-sequencing of tumor immune infiltrates and matched peripheral blood mononuclear cells of checkpoint inhibitor (CPI)-naive stage III-IV metastatic melanoma patients. After sample collection, the same patients received CPI-treatment and their response was assessed.
ORGANISM(S): Homo sapiens 
2024-04-08 | E-MTAB-13770 | biostudies-arrayexpress
TranscriptomicsScRNA-seq of healthy human PBMC samples treated with recombinant AAV8 or controls, assessed at multiple time-points
The study investigates the interaction between rAAV and the innate immune system. We conducted single cell RNA-sequencing (scRNA-seq) of PBMCs from six healthy human donors, comparing samples taken either before or after 1, 4 or 24 hrs of incubation with rAAV8. As a control, scRNA-seq was performed ...
ORGANISM(S): Homo sapiens 
2025-07-05 | E-MTAB-14760 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq and TCR-seq of Panc02-Fluc model with vehicle, anti PD1-IL2v, PD1, FAP-IL2v and PD1+FAP-IL2v treatment
Differentiating PD-1 + TCF-1 + stem-like CD8 T cells towards a distinct effector T cell population with enhanced anti-tumor and anti-viral efficacy by delivering an engineered IL-2 variant through PD-1 mediated cis-targeting; Single time point at termination (day 3 after 2nd Ab therapy); Tumor model...
ORGANISM(S): Mus musculus 
2022-06-13 | E-MTAB-11773 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq of human blood dendritic cells from buffy coats and in vitro differentiated dendritic cells from cord blood CD34 + stem cells
To compare human dendritic cells from peripheral blood, in vitro cultures with dendritic cells from human tumor tissues in publicly available single-cell RNA-seq datasets we performed single-cell RNA-seq of human blood dendritic cells and in vitro differentiated dendritic cells from cord blood CD34 ...
ORGANISM(S): Homo sapiens 
2022-06-15 | E-MTAB-11735 | biostudies-arrayexpress
Sort   by:  
 Page size