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UnknownImpaired Intestinal Permeability of Tricellular Tight Junctions in Patients with Irritable Bowel Syndrome with Mixed Bowel Habits (IBS-M).
Not available
S-EPMC9856377 | biostudies-literature
TranscriptomicsThe bromodomain protein BRD4 regulates splicing during heat shock
During heat stress cyto-protective genes including heat shock proteins are transcriptionally up-regulated and post-transcriptional splicing is inhibited. In contrast, co-transcriptional mRNA-splicing is maintained. These factors closely resemble the proteotoxic stress response during tumor developme...
ORGANISM(S): Homo sapiens 
2016-09-07 | E-GEOD-73471 | biostudies-arrayexpress
UnknownERG induces epigenetic activation of Tudor domain-containing protein 1 (TDRD1) in ERG rearrangement-positive prostate cancer.
Not available
S-EPMC3612037 | biostudies-literature
GenomicsGenome-wide DNA methylation events in TMPRSS2:ERG fusion negative prostate cancers implicate an EZH2 dependent mechanism with miRNA-26a hypermethylation.
Prostate cancer is the second most common cancer among men worldwide. Alterations in the DNA methylation pattern can be one of the leading causes for prostate cancer formation. This study is the first high throughput sequencing study investigating genome-wide DNA methylation patterns in a large coho...
ORGANISM(S): Homo sapiens 
2012-12-06 | E-GEOD-35342 | biostudies-arrayexpress
UnknownQSEA-modelling of genome-wide DNA methylation from sequencing enrichment experiments.
Not available
S-EPMC5389680 | biostudies-literature
TranscriptomicsHigh-throughput sequencing of matched colorectal normal, tumor and metastasis tissues and proof-of principal bioinformatics modeling of therapeutic consequences of miRNA applications
MiRNAs are discussed as diagnostic and therapeutic molecules. However, effective miRNA drug treatments with miRNAs are so far hampered by the complexity of the miRNA networks. To identify potential miRNA drugs in colorectal cancer, we profiled miRNA and mRNA expression in matching normal, tumor and ...
ORGANISM(S): Homo sapiens 
2013-09-18 | E-GEOD-46622 | biostudies-arrayexpress
UnknownTargeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity.
Not available
S-EPMC3192667 | biostudies-literature
UnknownAltered DNA Methylation Profiles in SF3B1 Mutated CLL Patients.
Not available
S-EPMC8431484 | biostudies-literature
UnknownDNA-methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancer.
Not available
S-EPMC3567140 | biostudies-literature
UnknownVesicular Release and Uptake of Circular LSD1-RNAs from Non-Cancer and Cancer Lung Cells.
Not available
S-EPMC10530930 | biostudies-literature
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