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TranscriptomicsAlternative Splicing in Erythropoiesis
Differentiating erythroid cells execute a unique gene expression program that insures synthesis of the appropriate proteome at each stage of maturation. Standard expression microarrays provide important insight into erythroid gene expression, but cannot detect qualitative changes in transcript struc...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-14588 | biostudies-arrayexpress
TranscriptomicsIdentification of Common Genetic Variants that Account for Transcript Isoform Variation between Human Populations
In addition to the differences between populations in transcriptional and translational regulation of genes, alternative pre-mRNA splicing (AS) is also likely to play an important role in regulating gene expression and generating variation in mRNA and protein isoforms. Recently, the genetic contribu...
ORGANISM(S): Homo sapiens 
2010-08-19 | E-GEOD-9703 | biostudies-arrayexpress
TranscriptomicsAlternative splicing in adult human heart and brain
RNA was obtained from Biochain, cDNA was synthesized using GeneChip WT cDNA Synthesis and Amplification kit (Affymetrix 900673) and hybridised to Affymetrix human high-resolution AltSplice microarrays.
ORGANISM(S): Homo sapiens 
2014-01-22 | E-MTAB-1911 | biostudies-arrayexpress
TranscriptomicsAlternative splicing in human temporal cortex
We analysed changes in transcript levels and alternative splicing in the temporal cortex of individuals of different ages that were cognitively normal, affected by frontotemporal lobar degeneration (FTLD), or affected by Alzheimer's disease (AD). Our experiment's purpose is to provide new insights i...
ORGANISM(S): Homo sapiens 
2012-04-27 | E-MTAB-656 | biostudies-arrayexpress
TranscriptomicsPosition-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB (HJAY)
To gain global insights into the role of the well-known repressive splicing regulator PTB we analyzed the consequences of PTB knockdown in HeLa cells using high-density oliogonucleotide splice-sensitive microarrays. The major class of identified PTB-regulated splicing event was PTB-repressed cassett...
ORGANISM(S): Homo sapiens 
2010-09-01 | E-GEOD-23513 | biostudies-arrayexpress
TranscriptomicsPosition-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB (Exon array)
To gain global insights into the role of the well-known repressive splicing regulator PTB we analyzed the consequences of PTB knockdown in HeLa cells using high-density oliogonucleotide splice-sensitive microarrays. The major class of identified PTB-regulated splicing event was PTB-repressed cassett...
ORGANISM(S): Homo sapiens 
2010-09-01 | E-GEOD-23514 | biostudies-arrayexpress
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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