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ProteomicsEarliest evidence of Neanderthal multifunctional bone tool production from cave lion (Panthera spelaea) remains
Scladina Cave, a key Middle Paleolithic site in Belgium, has yielded the earliest documented evidence of Neanderthals using cave lion bones as tools. This study focuses on stratigraphic Unit 5 (MIS 6), where four bone retouchers were identified. The diaphyseal fragment of the tibia reconstituted usi...
ORGANISM(S): Rhinocerotidae Ursus spelaeus Panthera spelaea Bos primigenius 
2025-07-04 | PXD055624 | Pride
Paleoproteomics Scladina cave Cave lion 
ProteomicsExtinct species identification from late Middle Pleistocene and earlier Upper Pleistocene bone fragments and tools not recognizable from their osteomorphological study by an enhanced proteomics protocol
Ancient preserved molecules offer the opportunity of gaining a deeper knowledge on their biological past. However, the development of a proteomic workflow remains a challenge. The analysis of fossils must involve a low quantity of material to avoid damaging the samples. In this study an enhanced pr...
ORGANISM(S): Mammalia 
2022-06-29 | PXD031386 | Pride
Pleistocene Palaeoproteomics Amino acids substitution Scladina cave Mass spectrometry Peptides modifications Mammalian bones Taxonomy 
UnknownNuclear DNA from two early Neandertals reveals 80,000 years of genetic continuity in Europe.
Not available
S-EPMC6594762 | biostudies-literature
ProteomicsNeanderthal exploitation of birds in north-western Europe: Avian remains from Scladina Cave (Belgium).
For a long time, Neanderthals were considered hunters of large mammals, whereas the diversification of the exploited faunal spectrum to include smaller taxa, including birds, was assumed to be specific to anatomically modern humans. In recent decades, archaeozoological analyses of faunal remains fro...
ORGANISM(S): Tetraoninae 
2024-09-03 | PXD051309 | Pride
Taphonomy Traceology Neanderthal-birds relationship Tool marks Middle paleolithic Use-wear analysis Archaeozoology 
GenomicsNuclear sequences from the Hohlenstein-Stadel and Scladina Neandertals
Nuclear DNA from two early Neandertals reveals 80,000 years of genetic continuity in Europe
PRJEB29475 | ENA
UnknownNew perspectives on Neanderthal dispersal and turnover from Stajnia Cave (Poland).
Not available
S-EPMC7479612 | biostudies-literature
UnknownA genetic analysis of the Gibraltar Neanderthals.
Not available
S-EPMC6681707 | biostudies-literature
ProteomicsPalaeoproteomics deconvolution of physical and genetic collagen mixtures
Species identification in palaeoproteomics relies on existing, often poor-quality, genome-derived protein sequences and lacks tools to cope with mixtures. Here, we address both challenges through the perspective of “physical and genetic mixtures”. Species that are absent from our database are consid...
ORGANISM(S): Parahyaena brunnea Hyaena hyaena Tragelaphus scriptus Aepyceros melampus Vulpes vulpes (Red fox) Crocuta crocuta (Spotted hyena) Bison bonasus Ceratotherium simum cottoni Panthera leo (Lion) Dugong dugon Tragelaphus strepsiceros Cygnus Mammuthus primigenius Martes foina Diceros bicornis Kobus kob thomasi Ursus Phacochoerus aethiopicus Carnivora Phoca vitulina Gazella dorcas Connochaetes gnou Proteles cristata Loxodonta africana (African elephant) Pusa sibirica Crocuta crocuta spelaea Giraffa camelopardalis Sus scrofa (Pig) Capreolus capreolus (Roe deer) Panthera pardus Panthera uncia Ursus spelaeus Palaeoloxodon Cervinae Dama dama Potamochoerus porcus Cervus elaphus (Red deer) Meles meles (Eurasian badger) Cervidae Panthera onca Panthera tigris sumatrae Tragelaphus spekii Sylvicapra grimmia Panthera pardus saxicolor Loxodonta cyclotis Ovis aries Equus quagga burchellii Boselaphus tragocamelus Vertebrata <Metazoa> Hippotragus niger Mustela putorius Rhinoceros unicornis Rangifer tarandus (Reindeer) (Cervus tarandus) Lepus sp. Elephas maximus Ammotragus lervia 
2026-09-17 | PXD079630 | Pride
Bioinformatics Bioarchaeology Palaeontology Palaeoproteomics Collagen 
UnknownClassification of Collagens via Peptide Ambiguation, in a Paleoproteomic LC-MS/MS-Based Taxonomic Pipeline.
Not available
S-EPMC11976868 | biostudies-literature
UnknownReevaluating the timing of Neanderthal disappearance in Northwest Europe.
Not available
S-EPMC7999949 | biostudies-literature
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