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UnknownThe Development and Characterization of a Next-Generation Oncolytic Virus Armed with an Anti-PD-1 sdAb for Osteosarcoma Treatment In Vitro.
Not available
S-EPMC10886739 | biostudies-literature
GenomicsMeiotic recombination cold spots in chromosomal cohesion sites [ChIP-Seq]
Meiotic chromosome architecture called M-bM-^@M-^\axis-loop structuresM-bM-^@M-^] and histone modifications have been demonstrated to regulate the Spo11-dependent formation of DNA double-strand breaks (DSBs) that trigger meiotic recombination. Using genome-wide chromatin immunoprecipitation (ChIP) a...
ORGANISM(S): Saccharomyces cerevisiae 
2014-03-31 | E-GEOD-52862 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung from wild type and Mt1(-/-)Mt2(-/-) double knock-out mice after nickel aerosol exposure for 3, 8, 24, 48, and 72 hrs
Wildtype and Mt1(-/-)Mt2(-/-) double knockout 129S1/SvImJ strain mouse lungs were compared in their response to nickel aerosol exposure at 3, 8, 24, 48, and 72 hrs.
ORGANISM(S): Mus musculus 
2006-08-02 | E-MEXP-816 | biostudies-arrayexpress
TranscriptomicsMolecular characterization of tumor cells from the cerebrospinal fluid and matched primary tumors from metastatic breast cancer patients with leptomeningeal disease
We purified tumor cells in the CSF (M-bM-^@M-^\CSFTCM-bM-^@M-^]) from 15 metastatic breast cancer patients diagnosed with leptomeningeal disease using a two-step method involving immunomagnetic enrichment and fluorescence-activated cell sorting (IE/FACS). Magnetic beads coated with mAb to the epithe...
ORGANISM(S): Homo sapiens 
2014-01-09 | E-GEOD-46068 | biostudies-arrayexpress
TranscriptomicsSequential waves of gene expression in patients with clinically defined Dengue illnesses reveal subtle disease phases and predict disease severity.
Background: Dengue virus (DENV) infection often leads to acute illness lasting 2-7 days with severity ranging from dengue fever (DF) to hemorrhagic fever (DHF) and fatal dengue shock syndrome (DSS). The dynamic changes of host responses on the gene transcription level that accompany DENV infection a...
ORGANISM(S): Homo sapiens 
2013-01-26 | E-GEOD-43777 | biostudies-arrayexpress
GenomicsGenome-wide mapping of meiotic double-strand breaks by sequencing Spo11 oligos.
The nonrandom distribution of meiotic recombination shapes patterns of inheritance and genome evolution, but chromosomal features governing this distribution are poorly understood. Formation of the DNA double-strand breaks (DSBs) that initiate recombination results in accumulation of Spo11 protei...
ORGANISM(S): Saccharomyces cerevisiae 
2011-03-07 | E-GEOD-26449 | biostudies-arrayexpress
TranscriptomicsEvalutation of the effect of ethanol upon gene expression in adult Drosophila melanogaster
This experiment was intended to determine if topical exposure to ethanol led to significant changes in gene expression in adult Drosophila melanogaster. It was determined that topical exposure to ethanol did not lead to a strong differential expression of genes in Drosophila after 4 hours. The eff...
ORGANISM(S): Drosophila melanogaster 
2010-06-11 | E-GEOD-3033 | biostudies-arrayexpress
UnknownEvolutionary hierarchies of conserved blocks in 5'-noncoding sequences of dicot rbcS genes.
Not available
S-EPMC1852302 | biostudies-literature
UnknownSex-Specific Outcomes of Transcatheter Edge-to-Edge Repair for Degenerative Mitral Regurgitation: Results From the CLASP IID Trial.
Not available
S-EPMC12462154 | biostudies-literature
UnknownThe novel SALT-M score predicts 1-year post-transplant mortality in patients with severe acute-on-chronic liver failure.
Not available
S-EPMC12036733 | biostudies-literature
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