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UnknownThe BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer.
Not available
S-EPMC5065110 | biostudies-literature
UnknownCombined BRAF and MEK Inhibition With Dabrafenib and Trametinib in BRAF V600-Mutant Colorectal Cancer.
Not available
S-EPMC4669588 | biostudies-literature
TranscriptomicsExpression data from EZH2 inhibitor treated Non-Hodgkins Lymphoma cell lines
Mutations within the catalytic domain of the histone methyltransferase (HMT) EZH2 have been identified in subsets of Non-Hodgkin Lymphoma (NHL) patients. These genetic alterations are hypothesized to confer an oncogenic dependency on EZH2 enzymatic activity in these cancers. We previously reported...
ORGANISM(S): Homo sapiens 
2014-02-19 | E-GEOD-49284 | biostudies-arrayexpress
UnknownPhase I Study of LY2606368, a Checkpoint Kinase 1 Inhibitor, in Patients With Advanced Cancer.
Not available
S-EPMC5321045 | biostudies-literature
TranscriptomicsRole of the prophages in the Staphylococcus aureus pathogenesis
Staphylococcus aureus is a Gram-positive human pathogen causing a variety of human diseases in both hospital and community settings. This bacterium is so closely associated with prophages that it is rare to find S. aureus isolates without prophages. Two phages are known to be important for staphyloc...
ORGANISM(S): Staphylococcus aureus 
2011-02-28 | E-GEOD-26623 | biostudies-arrayexpress
UnknownRandomized phase II, double-blind, placebo-controlled study of exemestane with or without entinostat in postmenopausal women with locally recurrent or metastatic estrogen receptor-positive breast cancer progressing on treatment with a nonsteroidal aromatase inhibitor.
Not available
S-EPMC4881332 | biostudies-literature
UnknownCRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 N141I neurons.
Not available
S-EPMC5660456 | biostudies-literature
UnknownOverall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer.
Not available
S-EPMC4672027 | biostudies-literature
TranscriptomicsExpression data from WT and Aire deficient mTECs
Aire is an important transcription regulator that mediates a role in central tolerance via promoting the promiscuous expression of tissue-specific antigens in the thymus. Although several mouse models of Aire-deficiency have been described, none has analysed the phenotype induced by a mutation that ...
ORGANISM(S): Mus musculus 
2009-03-15 | E-GEOD-14365 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling of the Calvaria from Conditional Hdac3 Defecient and Wild-type Mice
We utilized the Illumina MouseRef-8 gene expression technology to quantify differential gene expression between wildtype mice and mice with Osterix driven Cre conditional knockout of Hdac3 (Hdac3-CKO). We compared the RNA extracted from calvaria from 8 wildtype and 8 conditional knockout litter mat...
ORGANISM(S): Mus musculus 
2010-04-07 | E-GEOD-21087 | biostudies-arrayexpress
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