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TranscriptomicsSGEV_LRS
Comparison of genomic expression profiles in the mesenteric lymph nodes of naturally scrapie infected (clinical and preclinical stages) and control sheep. Expression profiles comparison of 7 clinical and 4 preclinical naturally scrapie infected sheep and 6 controls.
ORGANISM(S): Ovis aries 
2013-10-29 | E-MTAB-1346 | biostudies-arrayexpress
MetabolomicsMetabolomic study of disease progression in scrapie prion infected (RML) mice
Not available
ORGANISM(S): Mus musculus 
ST001291 | MetabolomicsWorkbench
TranscriptomicsSPGEV
Comparison of genomic expression profiles in the medulla oblongata of 4 preclinical naturally scrapie infected sheep and 6 controls.. The experiment consisted of the comparison of gene expression profiles in the medulla oblongata of preclinical scrapie and control sheep using oligoDNA CVI-Agilent c...
ORGANISM(S): Ovis aries 
2012-11-14 | E-MTAB-866 | biostudies-arrayexpress
TranscriptomicsIdentification of central nervous system genes involved in the host response to the scrapie agent.
In this study we identified genes differentially expressed in the central nervous system (CNS) of mice during infection with mouse-adapted scrapie agents. We used cDNA microarrays to examine gene expression profiles at early, mid (pre-clinical) and late (clinical) time points after inoculation. Keyw...
ORGANISM(S): Mus musculus 
2004-10-13 | E-GEOD-1840 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hippocampus of CV mice (C57Bl x VM/Dk) inoculated with ME7 scrapie to determine the molecular events that accompany the scrapie-associated hippocampal neuropathology
A study of differential gene expression in the hippocampus of CV mice (C57Bl x VM/Dk) inoculated with ME7 scrapie to determine the molecular events that accompany the scrapie-associated hippocampal neuropathology. Analysis was performed at 170 days post infection, a timepoint that coincides with se...
ORGANISM(S): Mus musculus 
2005-05-01 | E-MEXP-284 | biostudies-arrayexpress
TranscriptomicsGene profiling of mouse brain infected with scrapie strain 22A_End-point analysis
This SuperSeries is composed of the following subset Series: GSE12321: Brain_22A-Scrapie_End-point_PR04-39-to-46_using_GPL7118 GSE12322: Brain_22A-Scrapie_End-point_PR06-11-to-14_using_GPL7121 Refer to individual Series
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-12354 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in CNS after scrapie infection
Sheep scrapie is a transmissible spongiform encephalopathy (TSE), which are invariably fatalM- neurodegenerative diseases of the central nervous system (CNS). Accumulation of the misfolded prion protein, PrPSc in the CNS results in progressive neurodegenerative disease. Susceptible VRQ homozygous Ne...
ORGANISM(S): Ovis aries 
2014-06-01 | E-MTAB-2369 | biostudies-arrayexpress
UnknownPrion genotypes of scrapie-infected Canadian sheep 1998-2008.
Not available
S-EPMC2896806 | biostudies-literature
TranscriptomicsTranscriptome analysis of peripheral lymphoid tissue immediately before and after the detection of PrPSc in sheep scrapie
Sheep scrapie is a transmissible spongiform encephalopathy (TSE), which are invariably fatal neurodegenerative diseases of the central nervous system (CNS). Accumulation of the misfolded prion protein, PrPSc in the CNS results in progressive neurodegenerative disease. For many transmissible spongif...
ORGANISM(S): Ovis aries 
2014-02-20 | E-MTAB-2327 | biostudies-arrayexpress
UnknownAtypical scrapie isolates involve a uniform prion species with a complex molecular signature.
Not available
S-EPMC3214077 | biostudies-literature
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