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MetabolomicsAssessing the Feasibility of In Vitro Assays in Combination with Biological Matrices to Screen for Endogenous CYP450 Phenotype Biomarkers Using an Untargeted Metabolomics Approach—A Proof of Concept Study

Cytochrome P450 (CYP) enzymes are crucial for drug metabolism, yet inter-individual variability in their activity remains a significant clinical challenge. Current phenotyping methods are often impractical or even impossible, particularly in forensic toxicology and vulnerable populations. This pr...

2025-12-12 | MTBLS13325 | MetaboLights
UnknownFluid-Screen as a real time dielectrophoretic method for universal microbial capture.
Not available
S-EPMC8594773 | biostudies-literature
TranscriptomicsIn vivo screen of Francisella tularensis subsp. novicida mutants in sequence defined transposon library
We used an inhalation mouse model of infection to query a collection of 2149 mutants in a Francisella tularensis subsp. novicida background for genes required for growth, survival and systemic dissemination. A microarray-based genome-wide negative selection screen (Microarray tracking of transposon ...
ORGANISM(S): Francisella tularensis subsp. novicida 
2008-12-30 | E-GEOD-11297 | biostudies-arrayexpress
MetabolomicsPlasma metabolites of lipid metabolism associate with diabetic polyneuropathy in a cohort with screen-tested type 2 diabetes: ADDITION-Denmark
Not available
ORGANISM(S): Homo sapiens 
ST001411 | MetabolomicsWorkbench
MetabolomicsAn Airway Organoid-Based Screen Identifies a Role for the HIF1α-Glycolysis Axis in SARS-CoV-2 Infection
Not available
ORGANISM(S): Homo sapiens 
ST001921 | MetabolomicsWorkbench
TranscriptomicsAn RNAi Screen of Chromatin Proteins Identifies Tip60-p400 as a Regulator of Embryonic Stem Cell Identity
This SuperSeries is composed of the following subset Series: GSE11240: An RNAi Screen of Chromatin Proteins Identifies Tip60-p400 as a Regulator of Embryonic Stem Cell Identity, Experiment A GSE11241: An RNAi Screen of Chromatin Proteins Identifies Tip60-p400 as a Regulator of Embryonic Stem Cell Id...
ORGANISM(S): Mus musculus 
2008-07-11 | E-GEOD-11243 | biostudies-arrayexpress
MetabolomicsNon-targeted metabolomics screen comparing metabolite profiles of serum from PDAC-bearing mice that received metronidazole using high-resolution, high-performance LC-MS/MS analysis.
Not available
ORGANISM(S): Mus musculus 
ST002216 | MetabolomicsWorkbench
MetabolomicsA genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy(Part 1)
Not available
ORGANISM(S): Homo sapiens 
ST002085 | MetabolomicsWorkbench
MetabolomicsA genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy(Part 2)
Not available
ORGANISM(S): Homo sapiens 
ST002084 | MetabolomicsWorkbench
TranscriptomicsOligoarray comparative genomic hybridisation-mediated mapping of suppressors of an essential receptor tyrosine kinase generated in a deletion-biased mutagenesis screen
We have used oligoarray comparative genomic hybridization (aCGH) to identify novel suppressors generated in a UV-TMP based suppressor screen. This approach is suitable for detecting single gene mutations as well as copy number variations. Keywords: C.elegans Suppressor screen array CGH [1] 2 test s...
ORGANISM(S): Caenorhabditis elegans 
2012-07-12 | E-GEOD-15224 | biostudies-arrayexpress
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