Sort   by:  
 Page size 
TranscriptomicsEbf2 is a selective marker of brown and beige adipogenic precursor cells (Microarray)
Brown adipocytes, muscle and dorsal dermis descend from precursor cells in the dermomyotome, but the factors that regulate commitment to the brown adipose lineage are unknown. Here, we prospectively isolated and determined the molecular profile of embryonic brown preadipose cells. Brown adipogenic p...
ORGANISM(S): Mus musculus 
2014-09-16 | E-GEOD-60442 | biostudies-arrayexpress
TranscriptomicsEbf2 is a selective marker of brown and beige adipogenic precursor cells (RNA-seq)
Brown adipocytes, muscle and dorsal dermis descend from precursor cells in the dermomyotome, but the factors that regulate commitment to the brown adipose lineage are unknown. Here, we prospectively isolated and determined the molecular profile of embryonic brown preadipose cells. Brown adipogenic p...
ORGANISM(S): Mus musculus 
2014-09-16 | E-GEOD-60441 | biostudies-arrayexpress
TranscriptomicsPrdm16 Knockout Brown Adipose Tissue
Gene expression profile from brown adipose tissues of Prdm16 knockout and wile type mice. Prdm16 is a transcription factor that regulates the thermogenic gene program in brown and beige adipocytes. However, whether Prdm16 is required for the development or physiological function of brown adipose ti...
ORGANISM(S): Mus musculus 
2014-04-09 | E-GEOD-55080 | biostudies-arrayexpress
GenomicsCistromic and epigenomic changes in Prdm16 knock-out brown adipose tissue
Prdm16 is a transcription factor that drives a complete program of brown adipocyte differentiation, but the mechanism by which Prdm16 activates gene transcription remains unknown. Utilizing ChIP-seq teqhnique, we found that Prdm16 binds to chromatin at/near many brown fat-selective genes in BAT. Int...
ORGANISM(S): Mus musculus 
2015-02-10 | E-GEOD-63965 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of differentiated brown adipocytes from wild type, PGC-1 alpha knockout, or PGC-1 alpha knockout and PGC-1 beta knockdown mice to investigate the roles of PGC-1 coactivators in brown fat differentiation.
Mitochondria play an essential role in the ability of brown fat to generate heat, and the PGC-1 coactivators control several aspects of mitochondrial biogenesis. To investigate their specific roles in brown fat cells, we generated immortal preadipocyte lines from the brown adipose tissue of mice lac...
ORGANISM(S): Mus musculus 
2007-11-27 | E-GEOD-5042 | biostudies-arrayexpress
TranscriptomicsMitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
BAT transcriptome from control and brown adipocyte-specific Rev-erbα/β double knockout mice housed at thermoneutrality or cold-challenged for 6 hours. Brown adipose tissue (BAT) samples were collected from control and brown adipocyte-specific Rev-erbα/β double knockout mice (Ucp1-Cre; Nr1d1/2 fl/fl)...
ORGANISM(S): Mus musculus 
2026-09-23 | E-MTAB-17580 | biostudies-arrayexpress
TranscriptomicsMitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
Transcriptome from immortalized murine brown adipocytes BMC. Cells were transfected with siRNA construct #1 or construct #2 (pool) or non-targeting control on day 3 of differentiation and harvested on day 7 of differentiation.
ORGANISM(S): Mus musculus 
2026-09-23 | E-MTAB-17577 | biostudies-arrayexpress
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
Sort   by:  
 Page size