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ProteomicsA PEROXO-Tag enables rapid isolation of peroxisomes from human cells
Peroxisomes are metabolic organelles that perform a diverse array of critical functions in human physiology. Traditional isolation methods for peroxisomes can take more than one hour to complete and can be laborious to implement. To address this, we have now extended our prior work on rapid organell...
ORGANISM(S): Homo sapiens (Human) 
2020-05-20 | PXD018880 | Pride
Human hek-293t Peroxisome Peroxo-ip 
ProteomicsA PEROXO-Tag enables rapid isolation of peroxisomes from human cells
Peroxisomes are metabolic organelles that perform a diverse array of critical functions in human physiology. Traditional isolation methods for peroxisomes can take more than one hour to complete and can be laborious to implement. To address this, we have now extended our prior work on rapid organell...
ORGANISM(S): Homo sapiens (Human) 
2020-05-20 | PXD018918 | Pride
Human hek-293t Peroxisome 
TranscriptomicsTranscription profiling of expressed human chromosome 21 genes in transchromosomic mouse embryos carrying a freely segregating copy of Hsa21
Detection of expressed human chromosome 21 genes in transchromosomic mouse embryos carrying a freely segregating copy of Hsa21.
ORGANISM(S): Mus musculus 
2005-11-19 | E-MEXP-409 | biostudies-arrayexpress
TranscriptomicsHuman nuclear Dicer restricts the deleterious accumulation of endogenous double strand RNA
Dicer is a central enzymatic player in RNA interference (RNAi) pathways that acts to regulate gene expression in nearly all eukaryotes. Although the cytoplasmic function of Dicer is well documented in mammals, there is little known about any possible nuclear function. Here we show that Dicer is pre...
ORGANISM(S): Homo sapiens 
2014-04-10 | E-GEOD-56648 | biostudies-arrayexpress
UnknownAn engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration.
Not available
S-EPMC10541910 | biostudies-literature
TranscriptomicsIdentification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation
Identification of the coding elements in the genome is a fundamental step to understanding the building blocks of living systems. Short peptides (< 100 aa) have emerged as important regulators of development and physiology, but their identification has been limited by their size. We have leveraged t...
ORGANISM(S): Danio rerio 
2014-04-04 | E-GEOD-53693 | biostudies-arrayexpress
ProteomicsAn Outer Membrane Protein-Targeting Antibiotic Against Resistant Gram-Negative Bacterial Pathogens
There is an urgent need for novel antibiotics against carbapenem and 3rd generation cephalosporin-resistant Gram-negative pathogens, for which the last-resort antibiotics have lost most of their efficacy. We describe here a novel class of synthetic antibiotics that was inspired from natural product-...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2020-02-04 | MSV000084899 | MassIVE
UnknownTreatment adaptations and outcomes of patients experiencing inflammatory bowel disease flares during the early COVID-19 pandemic: the PREPARE-IBD multicentre cohort study.
Not available
S-EPMC9874879 | biostudies-literature
UnknownSafety, uptake, and use of a dapivirine vaginal ring for HIV-1 prevention in African women (HOPE): an open-label, extension study.
Not available
S-EPMC8038210 | biostudies-literature
UnknownAssessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study.
Not available
S-EPMC7906670 | biostudies-literature
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