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TranscriptomicsTranscriptional profiling of MLL5 Knock down vs. control C2C12 myoblasts (S phase enriched)
Knockdown of MLL5 led to deregulation of S phase. To understand the molecular basis for this phenotype, we performed microarray analysis of S phase synchronized myoblasts. Genes differentially regulated by MLL5 knock down were revealed by microarray analysis using NIA15K mouse chips. Control and kno...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-14931 | biostudies-arrayexpress
TranscriptomicsRNA-Seq profiling of C2C12 cells with exogenous expression of Mef2Da1 and Mef2Da2
Although splicing occurs in most multi-exon genes, the generation of distinct isoforms through the alternate use of mutually exclusive exons is less prevalent. As exon-switching events have the potential to give rise to isoforms with different cellular functions, we have explored the role of the mus...
ORGANISM(S): Mus musculus 
2013-06-03 | E-GEOD-46363 | biostudies-arrayexpress
GenomicsAlternate exon switching establishes a tissue-specific transcription factor to mediate temporal activation of gene expression during differentiation
Although splicing occurs in most multi-exon genes, the generation of distinct isoforms through the alternate use of mutually exclusive exons is less prevalent. As exon-switching events have the potential to give rise to isoforms with different cellular functions, we have explored the role of the mus...
ORGANISM(S): Mus musculus 
2013-06-01 | E-GEOD-43223 | biostudies-arrayexpress
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