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Transcriptomics3' RNA-seq of flies over-expressing cabut protein or RNAi against cabut mRNA
CbtOE (Tim-gal4; UAS-cbtFLAG), Tim-gal4 (control for CbtOE), cbtRNAi (Tim-gal4-UAS-Dcr2-UAS-cbtIR-cbtE1) and Tim-gal4;UAS-Dcr2 (control for CbtRNAi) flies. Flies were entrained in LD (light: dark) condition for 3-4 days and harvested at six time points: ZT3, ZT7, ZT11, ZT15, ZT19, ZT23 Fly heads we...
ORGANISM(S): Drosophila melanogaster 
2015-05-08 | E-GEOD-67590 | biostudies-arrayexpress
Transcriptomics3' RNA-seq of fly expressing cabut RNAi after exposure to different levels of sucrose
Control (+/cbtE1-UAS-cbt RNAi) or cabut RNAi flies (Tim-gal4, UAS-cbt RNAi) were starved for 16 hours and then exposed to food containing different concentrations of sucrose: 0, 25, 50 and 100 % for 18 hours. Fly heads were collected, RNA was extracted and RNA-seq libraries were prepared as prev...
ORGANISM(S): Drosophila melanogaster 
2015-05-08 | E-GEOD-58854 | biostudies-arrayexpress
UnknownA new in vivo model of pantothenate kinase-associated neurodegeneration reveals a surprising role for transcriptional regulation in pathogenesis.
Not available
S-EPMC3766815 | biostudies-literature
UnknownAssociation of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease.
Not available
S-EPMC6439872 | biostudies-literature
ModelsCasini2022 - genome scale metabolic model (iMTD22IC) of Methanothermobacter thermautotrophicus Delta H
(iMTD22IC) This model is described in these articles: Casini, I., McCubbin, T., Esquivel-Elizondo, S., Luque, G.G., Evseeva, D., Fink, C., Beblawy, S., Youngblut, N.D., Aristilde, L., Huson, D., Drager, A., Ley, R., Marcellin, E., Angenent, L.T., Molitor, B. 2023. An integrated systems biology app...
2026-03-15 | MODEL2211290001 | BioModels
FROG 
ModelsCasini2022 - Methanothermobacter thermautotrophicus Z-245
(iMTD22IC) This model is described in these articles: Casini, I., McCubbin, T., Esquivel-Elizondo, S., Luque, G.G., Evseeva, D., Fink, C., Beblawy, S., Youngblut, N.D., Aristilde, L., Huson, D., Drager, A., Ley, R., Marcellin, E., Angenent, L.T., Molitor, B. 2023. An integrated systems biology ap...
2026-03-15 | MODEL2211290002 | BioModels
FROG 
ModelsCasini2022 - Methanothermobacter marburgensis Marburg
This model is described in these articles: Casini, I., McCubbin, T., Esquivel-Elizondo, S., Luque, G.G., Evseeva, D., Fink, C., Beblawy, S., Youngblut, N.D., Aristilde, L., Huson, D., Drager, A., Ley, R., Marcellin, E., Angenent, L.T., Molitor, B. 2023. An integrated systems biology approach reveal...
2026-03-15 | MODEL2211290003 | BioModels
FROG 
TranscriptomicsRNAseq of human epithelial lung carcinoma cell line A549 exposed to ceria, silver or zinc ions, micron-sized particles or nanoparticles
The toxicity of silver and zinc oxide nanoparticles is hypothesised to be mediated by dissolved metal ions and cerium dioxide nanoparticles (CeO2 NPs) are hypothesised to induce toxicity specifically by oxidative stress dependant on their surface redox state. To test these hypotheses, RNAseq was app...
ORGANISM(S): Homo sapiens 
2018-02-01 | E-MTAB-5734 | biostudies-arrayexpress
TranscriptomicsIn vivo RNA interference RNAi target sequencing of Trypanosoma brucei
A direct comparison of RNAi in vitro with RNAi in vivo is being performed using RNA interference (RNAi) target sequencing (RIT-Seq) of Trypanosoma brucei to identify all genes specifically required for growth in vivo (the infectome). Assembly of the bloodstream-form T. brucei RNAi library and the R...
ORGANISM(S): Trypanosoma brucei 
2014-01-21 | E-ERAD-110 | biostudies-arrayexpress
TranscriptomicsRNA-seq of blood samples from patients diagnosed with visceral leishmaniasis and asymptomatic individuals (Brazil)
To ascertain which genes are involved in the outcome of Leishmania infantum infection and immunopathology of human visceral leishmaniasis (VL), we investigated the transcriptional profile of whole blood samples from patients diagnosed with active VL compared to asymptomatic individuals (positive ser...
ORGANISM(S): Homo sapiens 
2020-08-06 | E-MTAB-8818 | biostudies-arrayexpress
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