Sort   by:  
 Page size 
TranscriptomicsThe cohesin acetyltransferase Eco1 coordinates rDNA replication and transcription
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae 
2014-04-03 | E-GEOD-54743 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of gene expression changes in human A549 lung cancer cells upon siRNA knockdown of FAM60A and SDS3
The Sin3 histone deacetylase (HDAC) complex is a 1.2 MDa chromatin modifying complex that can repress transcription by binding to gene promoters and deacetylating histones. The Sin3/HDAC complex can affect cell cycle progression through multiple mechanisms and is among the targets of anticancer dru...
ORGANISM(S): Homo sapiens 
2012-09-15 | E-GEOD-39733 | biostudies-arrayexpress
TranscriptomicsGenome-wide replication analysis of a yeast eco1 mutant by deep sequencing.
Eco1 is the acetyltransferase that establishes sister-chromatid cohesion during DNA replication. Budding yeast with an eco1 mutation that genocopies Roberts syndrome displaysreduced ribosomal DNA (rDNA) transcription and a transcriptional signature of starvation. Weshow that deleting FOB1, a gene en...
ORGANISM(S): Saccharomyces cerevisiae 
2014-04-03 | E-GEOD-54742 | biostudies-arrayexpress
GenomicsPost-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation (ChIP-seq)
SAGA is a highly conserved transcriptional co-activator complex involved in multiple steps of transcription with activities that function both pre and post initiation. Loss of individual subunits results in developmental defects, suggesting a role in development. To better understand the roles of SA...
ORGANISM(S): Drosophila melanogaster 
2011-08-22 | E-GEOD-29513 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis comparing yeast Eco1 mutant W216G to mutants of FOB1 and RAD61
Eco1 is an acetyltransferase subunit of the cohesin complex and acts during DNA replication to establish cohesion between sister chromatids. However, cohesin has additional functions in gene expression, DNA damage repair, and higher-order organization of chromosomes. The eco1 mutant W216G disrupts a...
ORGANISM(S): Saccharomyces cerevisiae 
2014-04-03 | E-GEOD-54741 | biostudies-arrayexpress
GenomicsFunctional Evolution of the Yap/Yorkie Proto-oncogene and Elucidation of its Core Transcriptional Program
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2014-03-01 | E-GEOD-54603 | biostudies-arrayexpress
ProteomicsLC/MS Analysis of Myc-Affinity Captured, on-Beads Crosslinked, and on-Beads Digested S. cerevisiae SCC2 subunit of cohesin loading factor
Myc-Affinity Capture and on-Beads Crosslinking For each Saccharomyces cerevisiae strain (C-terminally myc-tagged Scc2 subunit of the cohesin loading factor complex or wild-type BY4741), 2x 3 L YPD medium (add 300 ml 20% Glucose to each 3 L of YPD before using) were separately inoculated in a 5L flas...
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2020-10-20 | MSV000086339 | MassIVE
TranscriptomicsSAHA Induced Dynamics of a Human Histone Deacetylase Protein Interaction Network
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-60125 | biostudies-arrayexpress
TranscriptomicsHsp90 Stress Potentiates Rapid Cellular Adaptation through Induction of Aneuploidy
This SuperSeries is composed of the following subset Series: GSE34085: Karyotype analysis of radicicol-resistant yeast colonies by array CGH (Radr1,2,3) GSE34086: Genome structure of radicicol-induced aneuploids in yeast by array CGH Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae 
2011-12-31 | E-GEOD-34087 | biostudies-arrayexpress
TranscriptomicsFunctional genomic analysis of the periodic transcriptome in the developing Drosophila wing.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2014-03-15 | E-GEOD-54928 | biostudies-arrayexpress
Sort   by:  
 Page size