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TranscriptomicsMechanisms of crystalline silica-induced pulmonary toxicity revealed by global gene expression profiling
This SuperSeries is composed of the following subset Series: GSE30178: Mechanisms of crystalline silica-induced pulmonary toxicity revealed by global gene expression profiling (rat lungs) GSE30180: Mechanisms of crystalline silica-induced pulmonary toxicity revealed by global gene expression profili...
ORGANISM(S): Homo sapiens 
2012-06-29 | E-GEOD-30216 | biostudies-arrayexpress
TranscriptomicsBlood gene expression profile of control and crystalline silica exposed rats
The present research aimed to investigate peripheral blood gene expression profiling as a minimally invasive surrogate approach to study silica-induced pulmonary toxicity. Rats were exposed to crystalline silica by inhalation (15 mg/m3, 6 hours/day, 5 days). Pulmonary damage and blood gene expressio...
ORGANISM(S): Rattus norvegicus 
2011-12-02 | E-GEOD-27023 | biostudies-arrayexpress
TranscriptomicsMechanisms of crystalline silica-induced pulmonary toxicity revealed by global gene expression profiling (A549 cells dataset 2)
A proper understanding of the mechanisms underlying crystalline silica-induced pulmonary toxicity has implications in the management and potential prevention of the adverse health effects associated with silica exposure including silicosis, cancer and several auto-immune diseases. Human lung type II...
ORGANISM(S): Homo sapiens 
2012-06-29 | E-GEOD-30200 | biostudies-arrayexpress
TranscriptomicsMechanisms of crystalline silica-induced pulmonary toxicity revealed by global gene expression profiling (A549 cells dataset 4)
A proper understanding of the mechanisms underlying crystalline silica-induced pulmonary toxicity has implications in the management and potential prevention of the adverse health effects associated with silica exposure including silicosis, cancer and several auto-immune diseases. Human lung type II...
ORGANISM(S): Homo sapiens 
2012-06-29 | E-GEOD-30214 | biostudies-arrayexpress
TranscriptomicsMechanisms of crystalline silica-induced pulmonary toxicity revealed by global gene expression profiling (A549 cells dataset 1)
A proper understanding of the mechanisms underlying crystalline silica-induced pulmonary toxicity has implications in the management and potential prevention of the adverse health effects associated with silica exposure including silicosis, cancer and several auto-immune diseases. Human lung type II...
ORGANISM(S): Homo sapiens 
2012-06-29 | E-GEOD-30180 | biostudies-arrayexpress
TranscriptomicsMechanisms of crystalline silica-induced pulmonary toxicity revealed by global gene expression profiling (A549 cells dataset 3)
A proper understanding of the mechanisms underlying crystalline silica-induced pulmonary toxicity has implications in the management and potential prevention of the adverse health effects associated with silica exposure including silicosis, cancer and several auto-immune diseases. Human lung type II...
ORGANISM(S): Homo sapiens 
2012-06-29 | E-GEOD-30213 | biostudies-arrayexpress
TranscriptomicsMechanisms of crystalline silica-induced pulmonary toxicity revealed by global gene expression profiling (A549 cells dataset 5)
A proper understanding of the mechanisms underlying crystalline silica-induced pulmonary toxicity has implications in the management and potential prevention of the adverse health effects associated with silica exposure including silicosis, cancer and several auto-immune diseases. Human lung type II...
ORGANISM(S): Homo sapiens 
2012-06-29 | E-GEOD-30215 | biostudies-arrayexpress
TranscriptomicsMechanisms of crystalline silica-induced pulmonary toxicity revealed by global gene expression profiling (rat lungs)
A proper understanding of the mechanisms underlying crystalline silica-induced pulmonary toxicity has implications in the management and potential prevention of the adverse health effects associated with silica exposure including silicosis, cancer and several auto-immune diseases. Human lung type II...
ORGANISM(S): Rattus norvegicus 
2012-06-29 | E-GEOD-30178 | biostudies-arrayexpress
TranscriptomicsTranscriptomics evaluation of hexavalent chromium toxicity in human dermal fibroblasts
Significant occupational and environmental exposures to hexavalent chromium, a metal with broad toxicity potential in humans, have been reported. In order to understand the mechanisms of dermal toxicity induced by hexavalent chromium, global gene expression profiling of human dermal fibroblasts expo...
ORGANISM(S): Homo sapiens 
2011-07-30 | E-GEOD-16349 | biostudies-arrayexpress
TranscriptomicsBlood gene expression of rats exposed to acetaminophen or methyl parathion
The purpose of this study was to investigate whether expression of specific genes in peripheral blood can be used as surrogate marker(s) to detect and distinguish target organ-specific chemical toxicity in rats. Rats were intraperitoneally administered a single, acute dose of a well-established hep...
ORGANISM(S): Rattus norvegicus 
2010-04-08 | E-GEOD-13442 | biostudies-arrayexpress
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