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GenomicsEGAS00001002091 - samples
Using sequencing and gene expression analyses, we identified a subgroup of HCA characterized by fusion of the INHBE and GLI1 genes and activation of sonic hedgehog pathway. Molecular subtypes of HCAs associated with different patients’ risk factors for HCA, disease progression, and pathology feature...
EGAD00001003092 | EGA
GenomicsA new subgroup of hepatocellular adenomas with sonic hedgehog pathway activation
Hepatocellular adenomas (HCA) are benign liver tumors divided in molecular subtypes characterized by mutations inactivating HNF1A, activating β-catenin or the IL-6/JAK/STAT inflammatory pathway. Molecular analyses of 533 HCA developed in 411 patients identified a new tumor subgroup with Sonic Hedgeh...
EGAS00001002091 | EGA
TranscriptomicsGene expression Classification of Colon Cancer defines six molecular subtypes with distinct clinical, molecular and survival characteristics [Expression]
From a clinical and molecular perspective, colon cancer (CC) is a heterogeneous disease but to date no classification based on high-density transcriptome data has been established. The aim of this study was to build up a robust molecular classification of mRNA expression profiles (Affymetrix U133Pl...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-39582 | biostudies-arrayexpress
TranscriptomicsGene expression Classification of Colon Cancer defines six molecular subtypes with distinct clinical, molecular and survival characteristics [CGH]
From a clinical and molecular perspective, colon cancer (CC) is a heterogeneous disease but to date no classification based on high-density transcriptome data has been established. The aim of this study was to build up a robust molecular classification of mRNA expression profiles (Affymetrix U133Pl...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-40966 | biostudies-arrayexpress
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