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In this study we examined the influence of seminal plasma on gene expression in human Ect1 ectocervical epithelial cells, and the extent to which recombinant TGFβ3 elicits comparable changes. Ect1 cells were incubated with recombinant human TGFβ3 (5 ng/ml), 10% pooled human seminal plasma (v/v), or ...
ORGANISM(S): Homo sapiens 
The seminal vesicles are male accessory sex glands that contribute the bulk of the seminal plasma in which mammalian spermatozoa are bathed during ejaculation. In addition to helping convey sperm through the ejaculatory duct, seminal vesicle secretions support sperm survival after ejaculation and in...
ORGANISM(S): Mus musculus (Mouse) 
2022-01-20 | PXD028564 | Pride
The objective of this study was to determine whether prostate cancer-associated miRNAs are present in seminal fluid and, if so, evaluate their diagnostic potential. Small RNA sequencing was used to profile and compare miRNAs in the non-sperm cellular fraction of seminal fluid from men with biopsy-pr...
ORGANISM(S): Homo sapiens 
Ejaculates contain a diverse mixture of sperm and seminal fluid proteins, the combination of which is crucial to male reproductive success under competitive conditions. Males should therefore tailor the production of different ejaculate components according to their social environment, with particul...
ORGANISM(S): Mus musculus (Mouse) 
2015-10-01 | PXD002900 | Pride
To examine the effect of seminal fluid on the whole genome expression profile of endometrial tissue following mating, RNA was extracted from endometrial tissue collected 8 h after CBAF1 females were mated with intact Balb/c males and compared to RNA from endometrial tissue of females mated with semi...
ORGANISM(S): Mus musculus 
Preparation of exosomes isolated from semen contain a substantial amount of RNA, mostly from 20 to 100 nucleotides in length. We sequenced separately 20-40 and 40-100 nucleotide fractions of RNA from exosomes isolated from semenal fluid from six healthy donors. We found various classes of small non...
ORGANISM(S): Homo sapiens 
Seminal fluid can have wide-ranging effects on reproductive fitness – from affecting sperm fertilisation capacity and female reproductive physiology, to influencing offspring viability and health. Seminal fluid can also change in response to environmental conditions including diet, which of itself i...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-23 | PXD073093 | Pride
A single cell atlas of the mouse seminal vesicle
Transcriptomic analysis of the seminal vesicle response to the reproductive toxicant acrylamide
During mammalian reproduction, sperm are delivered to the female reproductive tract bathed in a complex medium known as seminal fluid, which plays key roles in signaling to the female reproductive tract and in nourishing sperm for their onwards journey. The majority of seminal fluid is produced by a...
ORGANISM(S): Mus musculus 
2024-05-16 | GSE267191 | GEO
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