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ProteomicsCharacterisation and use of orthotopically grownHapT1tumours in its homologous host as a preclinical model to evaluate novel drugs against desmoplastic pancreatic cancer
The major objective of this study was to characterise theHapT1 orthotopic hamster pancreatic tumor as a preclinical model of desmoplastic pancreatic ductal adenocarcinoma; and use this model to validate the efficacy of drugs that kills activated pancreatic stellate cells (PSCs)in vitro. Experimental...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2018-10-26 | PXD003385 | Pride
Pancreatic cell line Hamster Lc-ms/ms 
ProteomicsQuantitative proteomics of hamster lung tissues infected with SARS-CoV-2 reveal host-factors having implication in the disease pathogenesis and severity
COVID-19 or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), appeared first in Wuhan, Hubei, China, has emerged as a global health concern claiming millions of lives worldwide. Syrian golden hamster (Mesocricetus auratus) has emerged as a suitable model as when infected by SARS-CoV-2, m...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Mesocricetus auratus (Golden hamster) 
2021-11-03 | PXD024547 | Pride
Quantitative proteomics Sars-cov-2 Tmt Inflammation Orbitrap Surfactant proteins 
TranscriptomicsRole of Macrophage migration inhibitory factor (MIF) in pancreatic stellate cells (PSCs)
The presence of activated pancreatic stellate cells (PSCs) in the pancreatic ductal adenocarcinoma (PDAC) microenvironment plays a significant role in cancer progression. Macrophage migration inhibitory factor (MIF) is overexpressed in PDAC tissues and expressed by both cancer and stromal cells. The...
ORGANISM(S): Mus musculus 
2022-09-28 | E-MTAB-9392 | biostudies-arrayexpress
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