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ProteomicsMS analysis of anti-Senp7 pulldown in adipocytes
To identify the function of Senp7 in adipocytes, we conducted a pulldown aasay and mass spectrometry analysis to identify proteins that interacted with Senp7.
ORGANISM(S): Mus musculus (Mouse) 
2024-06-16 | PXD043479 | Pride
Senp7 Adipocyte 
ProteomicsDeSUMOylase SENP7 mediated epithelial signaling triggers intestinal inflammation via expansion of Gamma-delta T cell
Inflammatory bowel disease (IBD) is a complex autoimmune disorder and recently shown to be associated with SUMOylation, a post-translational modification mechanism. Here we have identified a link between De-SUMOylases and tissue inflammation in IBD. SENP7, a deSUMOylase was seen to be explicitly upr...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-05-06 | PXD016018 | Pride
Desumoylases Ptms Sumoylation Inflammation Proteomics 
GenomicsSENP7 deSUMOylase-governed transcriptional program coordinates sarcomere assembly and is targeted in muscle atrophy
SENP7 deSUMOylase-governed transcriptional program coordinates sarcomere assembly and is targeted in muscle atrophy
PRJNA888055 | ENA
TranscriptomicsSENP7 deSUMOylase-governed transcriptional program coordinates sarcomere assembly and is targeted in muscle atrophy
Disorganization of the basic contractile unit of muscle cells i.e., the sarcomeres, leads to suboptimal force generation and is a hallmark of muscle atrophy. Here, we demonstrate that the nuclear role of SENP7 deSUMOylase is pivotal for sarcomere organization. SENP7 expression is temporally upregula...
ORGANISM(S): Mus musculus 
2026-06-30 | GSE214995 | GEO
ProteomicsDeSUMOylase SENP7 mediated epithelial signaling triggers intestinal inflammation via expansion of Gamma-delta T cell
Inflammatory bowel disease (IBD) is a complex autoimmune disorder and recently shown to be associated with SUMOylation, a post-translational modification mechanism. Here we have identified a link between De-SUMOylases and tissue inflammation in IBD. SENP7, a deSUMOylase was seen to be explicitly upr...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD015994 | Pride
Desumoylases Ptms Sumoylation Inflammation Proteomics 
UnknownStructure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7.
Not available
S-EPMC2581585 | biostudies-literature
UnknownSenp7 deficiency impairs lipid droplets maturation in white adipose tissues via Plin4 deSUMOylation.
Not available
S-EPMC11134554 | biostudies-literature
UnknownSENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing.
Not available
S-EPMC5271409 | biostudies-literature
UnknownSPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase.
Not available
S-EPMC4644472 | biostudies-literature
UnknownSwapping small ubiquitin-like modifier (SUMO) isoform specificity of SUMO proteases SENP6 and SENP7.
Not available
S-EPMC3195590 | biostudies-literature
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