Sensory neurons

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Unknown (7429)
Genomics (984)
Transcriptomics (973)
Proteomics (67)
Other (37)
Metabolomics (5)
Methylation profiling (3)
Models (2)
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Organisms

Mus musculus (690)
Homo sapiens (146)
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Drosophila melanogaster (47)
Caenorhabditis elegans (36)
Danio rerio (28)
Aplysia californica (9)
Macaca mulatta (7)
Sus scrofa (6)
Gallus gallus (5)
Nematostella vectensis (4)
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Cavia porcellus (3)
Apis mellifera (3)
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Haplochromis burtoni (2)
Petromyzon marinus (2)
Taeniopygia guttata (2)
Macaca nemestrina (2)
Macaca fascicularis (2)
synthetic construct (2)
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Arabidopsis thaliana (1)
Aurelia aurita (1)
Masticophis flagellum testaceus (1)
Corallus hortulana (1)
Crotalus atrox (1)

Organisms

Mus musculus (541)
Homo sapiens (94)
Rattus norvegicus (45)
Drosophila melanogaster (29)
Caenorhabditis elegans (28)
Danio rerio (22)
Macaca mulatta (5)
Sus scrofa (5)
Aplysia californica (3)
Nematostella vectensis (3)
Gallus gallus (3)
Taeniopygia guttata (2)
Cavia porcellus (2)
Apis mellifera (2)
Ciona intestinalis (2)
Ooceraea biroi (1)
Haplochromis burtoni (1)
Vanessa cardui (1)
Hirudo verbana (1)
Petromyzon marinus (1)
Protopterus amphibius (1)
Human alphaherpesvirus 1 (1)
Macaca nemestrina (1)
Xenopus laevis (1)
Sminthopsis crassicaudata (1)
Macaca fascicularis (1)
Ambystoma mexicanum (1)
Oikopleura dioica (1)
Canis lupus familiaris (1)
Mus (1)

Repository

ENA (937)
geo (790)
biostudies-arrayexpress (260)
pride (44)
MassIVE (19)
EGA (8)
MetaboLights (3)
ExpressionAtlas (2)
BioModels (2)
dbGaP (2)
GNPS (2)
iProX (2)
jPOST (2)

Tissue

Brain (13)
Cell culture (9)
Neuron (5)
Venom (3)
Electrically active cell (2)
Embryonic stem cell (2)
Liver (2)
Permanent cell line cell (2)
Sensory neuron of dorsal root ganglion (2)
Nodose ganglion visceral sensory neurons (1)
Dorsal root ganglion visceral sensory neurons (1)
Amygdala (1)
Blood serum (1)
Dendritic cell (1)
Dorsal root ganglion (1)
Fibroblast (1)
Ganglion cell layer (1)
Hippocampal formation (1)
Mechanoreceptor cell (1)
Nerve (1)
Nerve cord (1)
Olfactory bulb (1)
Olfactory receptor neuron (1)
Pain receptor cell (1)
Peripheral ganglion (1)
Peripheral nerve (1)
Sensory neuron (1)
Sensory processing neuron (1)
Skin (1)
Spinal cord (1)

Disease

Parkinson's disease (2)
Disease free (2)
Diabetes, diabetic peripheral neuropathy (1)
Not applicable (1)
Normal (1)
Fragile X syndrome (1)
Head and neck squamous cell carcinoma (1)
Herpes simplex (1)
Neuroblastoma (1)
Neuropathy (1)
Sciatic nerve (1)
Sensory peripheral neuropathy (1)

Technology Type

Mass Spectrometry (44)
Shotgun proteomics (19)
Bottom-up proteomics (13)
Data-dependent acquisition (6)
Data-independent acquisition (5)
Top-down proteomics (5)
Gel-based experiment (4)
Affinity purification coupled with mass spectrometry proteomics (3)
DiaPASEF (2)
ILLUMINA, Illumina MiSeq, Illumina HiSeq 2000 (1)
Illumina HiSeq 2500 (1)
NMR spectroscopy (1)
Mass spectrometry assay (1)
Mass spectrometry (1)
Affinity proteomics (1)
SWATH MS (1)

Instrument Platform

Illumina HiSeq 2500 (17)
Orbitrap Fusion Lumos (8)
Illumina NovaSeq 6000 (7)
NextSeq 550 (5)
Illumina HiSeq 2000 (5)
Illumina HiSeq 4000 (5)
NextSeq 500 (4)
HiSeq X Ten (3)
Orbitrap Fusion (3)
Single-Cell Extraction: For enzymatic digestion, pronase (Septomyces argeus, 1 mg/mL) was applied for 25 minutes at room temperature for P0 to P8 datasets. Cells were dissociated and triturated into a single-cell suspension in ACSF supplemented with 1% fetal calf serum (FCS) and DNase (1 µL/10 mL). Trituration was performed using three glass Pasteur pipettes of decreasing diameters. For P30 datasets, enzymatic digestion and cell dissociation were carried out using the Worthington Papain Dissociation System, following the manufacturer’s instructions. Single-Nuclei Extraction: For nuclei isolation, the Hibernate™-E Medium was removed, and 500 µL of chilled 0.1X NP40 Lysis Buffer was added. Tissue was homogenized using a Pellet Pestle (15 strokes) and incubated on ice for 5 minutes. The suspension was pipette-mixed 10 times using a wide-bore pipette tip and incubated for an additional 10 minutes on ice. Following lysis, 500 µL of chilled wash buffer was added, and the mixture was pipette-mixed 5 times using a regular-bore pipette tip. The suspension was filtered through a 30 µm cell strainer into a 50 mL tube to remove debris. The filtered suspension was transferred to a 1.5 mL tube and centrifuged at 950 × g for 10 minutes at 4°C. The supernatant was carefully removed, and the nuclei pellet was retained for downstream analysis. (2)
Illumina MiSeq (2)
Orbitrap Exploris 480 (2)
Q Exactive (2)
Q Exactive HF (2)
TripleTOF 5600 (2)
Chromium Next GEM Chip G (1)
10X v3 (1)
Qubit 3.0 and Nanodrop Lite (1)
Illumina HiSeq 1000 (1)
AB 5500xl Genetic Analyzer (1)
6550 iFunnel Q-TOF LC/MS (1)
LTQ Orbitrap Elite (1)
LTQ Velos (1)
Orbitrap Eclipse (1)
Q Exactive Plus (1)
Q-Exactive (1)
Liquid Chromatography MS - Alternating (LC-MS (Alternating)) (1)
Nuclear Magnetic Resonance (NMR) - (1)
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Liquid Chromatography MS - positive - reverse phase (1)

Publication Date

2025 (157)
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2022 (72)
2020 (58)
2014 (48)
2015 (47)
2016 (43)
2013 (40)
2019 (35)
2018 (34)
2017 (29)
2011 (29)
2012 (27)
2010 (27)
2008 (22)
2007 (18)
2009 (13)
2006 (8)
2005 (7)
2004 (1)

CHEBI ID

CHEBI:18237 (2)
CHEBI:44897 (2)
CHEBI:16919 (2)
CHEBI:17234 (2)
CHEBI:26689 (1)
CHEBI:17287 (1)
CHEBI:57579 (1)
CHEBI:422 (1)
CHEBI:4170 (1)
CHEBI:29101 (1)
CHEBI:28087 (1)
CHEBI:16027 (1)
CHEBI:17138 (1)
CHEBI:15361 (1)
CHEBI:15422 (1)
CHEBI:16761 (1)
CHEBI:16908 (1)
CHEBI:16526 (1)
CHEBI:15846 (1)
CHEBI:18021 (1)
CHEBI:16830 (1)
CHEBI:66860 (1)
CHEBI:66855 (1)
CHEBI:18139 (1)
CHEBI:66854 (1)
CHEBI:16016 (1)
CHEBI:33984 (1)
CHEBI:28315 (1)
CHEBI:30813 (1)
CHEBI:66847 (1)

Metabolite Name

2-(2,5-dihydroxy-4-methoxyphenyl)-3,5,6,7-tetrahydroxy-3,4-dihydro-2H-1-benzopyran-4-one; 3-(2,5-dihydroxy-4-methoxyphenyl)-1-(2,3,4,6-tetrahydroxyphenyl)propane-1,2-dione; 3,5,7-trihydroxy-6-methoxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; 3,5,7-trihydroxy-6-methoxy-2-(2,3,4-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; 3,5,7-trihydroxy-6-methoxy-2-(2,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; (1)
N-acetyl-L-2-aminoadipate(2-); (1)
VI2Fuc-nLc6; (1)
3',5'-Diiodo-L-thyronine 4'-O-sulfate; (1)
TG(22:1(13Z)/19:2n6/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); (1)
TG(15:0/22:2(13Z,16Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); TG(15:0/22:4(7Z,10Z,13Z,16Z)/22:4(7Z,10Z,13Z,16Z)); TG(15:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:2(13Z,16Z)); TG(22:2(13Z,16Z)/15:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); TG(22:4(7Z,10Z,13Z,16Z)/15:0/22:4(7Z,10Z,13Z,16Z)); (1)
TG(14:0/15:0/24:0); TG(14:0/24:0/15:0); TG(15:0/14:0/24:0); TG(15:0/16:0/22:0); TG(15:0/18:0/20:0); (1)
Shoyuflavone C; (1)
4-Hydroxycinnamoylagmatine; (1)
Tipranavir; (1)
N-Acetyltryptophan; Methylphenobarbital; Nigellicine; cyclic 6-Hydroxymelatonin; (1)
Sialyllacto-N-tetraose a; Sialyllacto-N-neotetraose c; Sialyllacto-N-tetraose b; LS tetrasaccharide d; Sialyllacto-N-tetraose c; (1)
Ganglioside GD3 (d18:1/12:0); (1)
L-Tryptophan; D-Tryptophan; 3-Hydroxymethylantipyrine; Ethotoin; (Â±)-Tryptophan; (1)
Vinylacetylglycine; Trimethadione; 5-ethyl-5-methyl-2,4-oxazolidinedione; 6-Oxopiperidine-2-carboxylic acid; (1)
Glutamyltryptophan; Tryptophyl-Glutamate; gamma-Glutamyltryptophan; (1)
Norlaudanosoline; Pipermethystine; noroxymorphone; (1)
Ethyl 2-mercaptopropionate; Methyl 3-mercaptobutanoate; Methyl 3-(methylthio)propanoate; Ethyl 2-(methylthio)acetate; Ethyl 3-mercaptopropanoic acid; (1)
Olmesartan; (1)
De-O-methylsterigmatocystin; Aurantricholide B; {3-[2-(3,5-dihydroxyphenyl)ethyl]phenyl}oxidanesulfonic acid; Dihydroresveratrol 3-sulfate; Dihydroresveratrol 4'-sulfate; (1)
1-Isothiocyanato-8-(methylthio)octane; (1)
PA(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/24:1(15Z)); PA(24:1(15Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); (1)
Zizybeoside I; Armillaricin; Benzyl gentiobioside; 15beta-hydroxycyproterone acetate; (1)
6,8-bis[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-yl]-2-(3-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; 8-[3,7-dihydroxy-2-(3-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-yl]-2-(3,4-dihydroxyphenyl)-6-[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-yl]-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; 6-[3,7-dihydroxy-2-(3-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-yl]-2-(3,4-dihydroxyphenyl)-8-[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-yl]-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; (1)
Simmondsin 2'-ferulate; Astin I; 4-Hydroxytamoxifen-N-glucuronide; 6-{[1-(2-{[3-(3,4-dimethoxyphenyl)-1-hydroxypropylidene]amino}ethyl)-3-methoxy-4-oxocyclohexa-2,5-dien-1-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid; 6-{[1-(2-{[2-(3,4-dimethoxyphenyl)ethyl]-C-hydroxycarbonimidoyl}ethyl)-3-methoxy-4-oxocyclohexa-2,5-dien-1-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid; (1)
Indolelactic acid; 5-Methoxyindoleacetate; Cinnamoylglycine; Edulitine; Methyl 1-methoxy-1H-indole-3-carboxylate; (1)
P-Cresol glucuronide; 2-O-Benzoyl-D-glucose; D-Vacciniin; (1)
(Â±)-Ribaline; 5-Amino-6-(4-hydroxy-2-butenoyl)-2,2-dimethyl-4-chromanone; (1)
CD 1790; (1)
Tetraphyllin B; (1)

IsPrivate

False (2)

First Public Date

2025 (165)
2024 (131)
2026 (127)
2023 (85)
2021 (75)
2022 (71)
2014 (70)
2020 (65)
2017 (36)
2019 (34)
2018 (33)
2016 (18)
2015 (16)
2013 (11)

Classification

viruses (1)

Modelling Approach

Ordinary differential equation model (2)

Study type

Transcription profiling by array (153)
RNA-seq of coding RNA (64)
RNA-seq of coding RNA from single cells (14)
ChIP-chip by tiling array (5)
Unknown experiment type (4)
Transcription profiling by tiling array (4)
Cell line - High-throughput sequencing (2)
ChIP-seq (2)
Methylation profiling by high throughput sequencing (2)
RNA-seq of non coding RNA (2)
Cell line - Single-cell sequencing (1)
Differential (1)
Animal - High-throughput sequencing (1)
Transcription profiling by RT-PCR (1)
Spatial transcriptomics by high-throughput sequencing (1)
Other (1)
CUT&RUN (1)
RNA-seq of total RNA (1)

Release Date

2025 (743)
2023 (663)
2024 (631)
2022 (623)
2021 (601)
2020 (541)
2018 (484)
2019 (432)
2017 (393)
2016 (393)
2015 (369)
2014 (309)
2012 (222)
2013 (221)
2011 (210)
2010 (183)
2009 (149)
2008 (138)
2007 (86)
2026 (68)
2006 (48)
2004 (42)
2003 (31)
2005 (29)
2001 (18)
2002 (17)
1998 (13)
2000 (11)
1999 (11)
1997 (7)

Lab affiliation

Department of Cell Biology, Harvard Medical School, Boston MA 02115 (2)
Imperial College, Medicine, Level 3 Sherfield Building, Exhibition Road, SW7 2AZ London (2)
Institute of Clinical Pharmacology, Goethe-University, Frankfurt am Main, Germany (2)
University of Vienna (2)
- Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Portugal - ICVS/3B’s Associate Lab, PT Government Associated Lab, Portugal (1)
Centre for Discovery Brain Sciences, University of Edinburgh, UK; Simons Initiative for the Developing Brain, University of Edinburgh, UK (1)
Core Unit Proteomics, Berlin Institute of Health at Charite-Universitaetsmedizin Berlin and Max Delbrueck Center for Molecular Medicine, Berlin, Germany (1)
Department of Biophysics, National Institute of Mental Health and Neurosciences (NIMHANS). India. (1)
Department of Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany (1)
Department of Immunobiology, College of Life Science and Technology, Jinan University, Guangzhou, China. (1)
Department of Neuro- and Sensory Physiology University Medical Center Göttingen Humboldtallee 23 37073 Göttingen (1)
Department of Neurobiology, Harvard Medical School; Boston, USA. (1)
Faculty Scientist,Institute of Bioinformatics, International Technology Park, Bangalore 560066, India (1)
German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany (1)
Group Leader, Institute for Molecular Biosciences, The University of Queensland, Australia (1)
Immunobiology of Infection Unit,Institut Pasteur, 75015 Paris, France (1)
Institute for Genetics and CECAD Research Center, University of Cologne, Joseph-Stelzmann Str. 26, 50931 Cologne, Germany (1)
Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia. (1)
Institute for Molecular Bioscience, University of Queensland; QLD 4072, Australia (1)
Institute for Molecular Biosciences, The University of Queensland (1)
Max-Delbrück Center (1)
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Spatial Proteomics Group, Berlin, Germany (lab head) (1)
Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne (1)
Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne Germany (1)
Medizinisches Proteom-Center, Ruhr-Universität Bochum, ZKF 1.055, Universitätsstraße 150, 44801 Bochum, Germany (1)
Montpellier Hospital (1)
Munich Cluster for Systems Neurology (SyNergy Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany. (1)
Peking University (1)
Population Health Sciences, Virginia Maryland College of Veterinary Medicine, Virginia Polytechnic Institute & State University (1)
Primary Investigator, Assistant Professor, Division of Biosciences, College of Dentistry, Ohio State University (1)

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Expression data from FACS purified nociceptor neurons from peripheral sensory ganglia

The goal of this study was to analyze global gene expression in specific populations of nociceptor sensory neurons, the neurons that detect damaging/noxious stimuli. The dorsal root ganglia (DRG), trigeminal ganglia, and nodose ganglia are anatomically distinct peripheral sensory ganglia that contai...

ORGANISM(S): Mus musculus

2013-08-28 | E-GEOD-46546 | biostudies-arrayexpress

Transcription profiling of olfactory epithelia isolated from wild type and KLF7 null mice to identify potential KLF7 target genes in olfactory sensory neurons.

KLF7 null mice show profound axonal growth defects in the olfactory epithelium. The goal of this study was the identification of potential KLF7 target genes in olfactory sensory neurons. Experiment Overall Design: Olfactory epithelia were isolated from 3 wildtype and 3 mutant 1 day old pups and the ...

ORGANISM(S): Mus musculus

2007-12-01 | E-GEOD-3595 | biostudies-arrayexpress

Gene expression in cellular compartments of Aplysia sensory neurons

Whole genome transcriptional profiling is used to compare ESTs found in cell bodies and processes of Aplysia sensory neurons RNA samples derived from cell bodies or processes of Aplysia single cultured sensory neurons were hybridized to custom Aplysia EST microarrays. Two-condition experiment; four ...

ORGANISM(S): Aplysia californica

2013-04-26 | E-GEOD-30388 | biostudies-arrayexpress

Mapping regulatory variation in sensory neurons using IPS lines from the HIPSCI project

Sensory neurons are nerve cells that are activated by sensory input such as heat, light and convey information to the brain. Although a key cell type in complex organisms, human sensory neurons are challenging to study because they are impossible to obtain from living donors. We have collaborated wi...

EGAS00001001149 | EGA

Derivation of sensory neurons from iPSCs.

Characterization of the gene expression changes accompanying the differentiation of hPSC-sensory from embryonic stem cells through to neuronal precursor cells. We also compare the time course gene expression profile to that of the relevant primary human tissue, human dorsal root ganglia (hDRG). A re...

ORGANISM(S): Homo sapiens

2014-10-22 | E-MTAB-3031 | biostudies-arrayexpress

Transcription profiling of murine neurons in the nodose and dorsal root ganglia to elucidate molecular characteristics of different sensory neorons.

Vagal afferent neurons are thought to convey primarily physiological information, whereas spinal afferents transmit noxious signals from the viscera to the central nervous system. In order to elucidate molecular identities for these different properties, we compared gene expression profiles of neu...

ORGANISM(S): Mus musculus

2007-08-31 | E-GEOD-2917 | biostudies-arrayexpress

The transcriptome of TRPV1-positive sensory neurons revealed by subgroup-elimination transcriptomics

We developed an approach to rapidly eliminate the subgroup of sensory neurons expressing the heat-gated cation channel TRPV1 from dissociated rat sensory ganglia using agonist treatment followed by density centrifugation. To identify transcripts predomintly expressed in TRPV1-positive neurons, we co...

ORGANISM(S): Rattus norvegicus

2015-05-12 | E-GEOD-59727 | biostudies-arrayexpress

Transcription profiling of mouse olfactory sensory neurons

The overall aim of the experiment is to understand the phenotype of mature mouse olfactory sensory neurons by analyzing the transcripts expressed and enriched in them as compared to the rest of the cell types in the olfactory epithelium (consisting of immature neurons, supporting cells, progenitor c...

ORGANISM(S): Mus musculus

2008-06-13 | E-GEOD-4915 | biostudies-arrayexpress

Rat sensory and motor nerve fibroblasts LC-MSMS

In this study, a quantitative proteomic technique based on isobaric tags for relative and absolute quantitation (iTRAQ) was used to compare the proteome of cultured sensory and motor nerve fibroblasts (Fbs). Among a total of 2597 overlapping proteins identified, we obtained 148 differentially expres...

ORGANISM(S): Rattus norvegicus (Rat)

2023-03-11 | PXD034827 | Pride

Transcription profiling of mouse spinal and trigeminal sensory ganglia of Brn3a knockout and wild type mice reveals conserved and distinct regulatory targets of Brn3a at different levels of the sensory axis

General somatic sensation is conveyed to the central nervous system at cranial levels by the trigeminal ganglion (TG), and at spinal levels by the dorsal root ganglia (DRG). Although these ganglia have similar functions, they have distinct embryological origins, in that both contain neurons origina...

ORGANISM(S): Mus musculus

2008-06-14 | E-GEOD-5658 | biostudies-arrayexpress

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