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MetabolomicsMetabolomics profiling of pre-and post-anesthesia plasma samples obtained via Ficoll separation
1H Nuclear Magnetic Resonance (NMR) spectroscopy was used to investigate the metabolic consequences of general anesthesia in the plasma of two groups of patients with diagnosis for non-metastatic colorectal cancer and metastatic colorectal cancer with liver-metastasis, respectively. Patients were tr...
2015-11-17 | MTBLS172 | MetaboLights
MetabolomicsDivalent Aptamer-mediated Clustering for Extracellular Vesicle Separation
Extracellular vesicles (EVs) are important mediators of intercellular communication and promising sources of diagnostic and therapeutic biomarkers, yet effective EV isolation remains challenging due to trade-offs among yield, purity, and adaptability across biofluids. Here, we introduce divalent apt...
2026-05-04 | MTBLS14425 | MetaboLights
MetabolomicsPROMIS, global analysis of PROtein-Metabolite Interactions using Size separation in Arabidopsis thaliana
Small molecules not only represent cellular building blocks and metabolic intermediates, but also regulatory ligands and signaling molecules that interact with proteins. Although these interactions affect cellular metabolism, growth, and development, they have been largely understudied. Herein, we d...
2018-07-19 | MTBLS94 | MetaboLights
MetabolomicsRIOK1 Phase Separation Shapes Stress Adaptation and Cell Fate in Hepatocellular Carcinoma

Cancer cells can always be unexpected rescued from desperate environment by mounting adaptive responses to resolve the arising cellular stress. The dynamic stress granules (SGs) assembly and metabolic reprogramming play crucial roles in maintaining cellular growth and homeostasis. However, the me...

2025-02-26 | MTBLS11963 | MetaboLights
TranscriptomicsExtraction of high-quality epidermal RNA after NH4SCN induced dermo-epidermal separation of 4 mm human skin biopsies
To obtain a separation of the epidermal and dermal compartments in order to examine compartment specific biological mechanisms in the skin we incubated 4 mm human skin punch biopsies in ammonium thiocyanate (NH4SCN). We wanted to test 1) the histological quality of the dermo-epidermal separation obt...
ORGANISM(S): Homo sapiens 
2010-03-03 | E-GEOD-15101 | biostudies-arrayexpress
TranscriptomicsCD138-positive cell separation affects cancer gene expression in human myeloma cell lines
Gene expression (GE) profiling of multiple myeloma (MM) cells is a promising means of identifying high-risk MM patients. The analyses depend on plasma cell purification by CD138+ cell separation. Considering the sensitivity of gene transcription, we wanted to test if cell separation distorts true in...
ORGANISM(S): Homo sapiens 
2012-03-01 | E-MEXP-2961 | biostudies-arrayexpress
GenomicsPantoea vagans strain:Separation from Tobacco | isolate:Separation from Tobacco
Pantoea vagans strain:Separation from Tobacco | isolate:Separation from Tobacco Genome sequencing
PRJNA1127695 | ENA
GenomicsStenotrophomonas maltophilia strain:Separation from Tobacco | isolate:Separation from Tobacco
Stenotrophomonas maltophilia strain:Separation from Tobacco | isolate:Separation from Tobacco Genome sequencing
PRJNA1127700 | ENA
TranscriptomicsInvolvement of the brain renin-angiotensin system in the effects of maternal separation
The postnatal development of the mouse is characterized by a stress hyporesponsive period (SHRP), where basal corticosterone levels are low and responsiveness to mild stressors is reduced. Maternal separation is able to disrupt the SHRP and is widely used to model early trauma. In this study we aime...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-14687 | biostudies-arrayexpress
GenomicsEnhanced Phase Separation Mediated Oncogenicity [HiC]
Enhanced Phase Separation Mediated Oncogenicity [HiC]
PRJNA1003850 | ENA
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