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ProteomicsSUMOylation of Protein Phosphatase 5 Regulates Phosphatase Activity and Substrate Release
The serine/threonine protein phosphatase 5 (PP5) regulates hormone and stress-induced signaling networks. PP5 has been suggested to exist largely in a ‘closed’ and autoinhibitory state whereas the ‘open’ conformation is required for activity. Additionally, PP5 is subject to post-translational modifi...
ORGANISM(S): Homo sapiens (Human) 
2023-09-08 | PXD038701 | Pride
Chaperone Ulk1 Chaperone code Hsp90 Atg1 Autophagy Phosphorylation 
ProteomicsQuantitative chemical proteomic profiling of phosphoprotein phosphatases
We have developed a chemical proteomic strategy for the systematic interrogation of endogenous phosphoprotein phosphatases (PPP) and their interacting proteins, including regulatory and scaffolding subunits, and substrates (the 'PPPome'). PPPs are captured using an immobilized non-selective PPP inhi...
ORGANISM(S): Neurospora Crassa (ncbitaxon:5141) Candida Albicans (ncbitaxon:5476) Saccharomyces Cerevisiae (ncbitaxon:4932) Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) Schizosaccharomyces Pombe (ncbitaxon:4896) 
2017-07-07 | MSV000081226 | MassIVE
UnknownThe role of serine/threonine protein phosphatase type 5 (PP5) in the regulation of stress-induced signaling networks and cancer.
Not available
S-EPMC2493293 | biostudies-literature
UnknownSelective activators of protein phosphatase 5 target the auto-inhibitory mechanism.
Not available
S-EPMC4721540 | biostudies-literature
UnknownThe Inhibition of Serine/Threonine Protein Phosphatase Type 5 Mediates Cantharidin Toxicity to Control Periplaneta americana (L.).
Not available
S-EPMC7600710 | biostudies-literature
UnknownSerine/Threonine Protein Phosphatase-5 Accelerates Cell Growth and Migration in Human Glioma.
Not available
S-EPMC11486260 | biostudies-literature
UnknownSUMOylation of protein phosphatase 5 regulates phosphatase activity and substrate release.
Not available
S-EPMC11549447 | biostudies-literature
UnknownStructure and function of the co-chaperone protein phosphatase 5 in cancer.
Not available
S-EPMC7193036 | biostudies-literature
UnknownStructural and functional basis of protein phosphatase 5 substrate specificity.
Not available
S-EPMC4987771 | biostudies-literature
UnknownProtein phosphatase 5 protects neurons against amyloid-beta toxicity.
Not available
S-EPMC3044491 | biostudies-literature
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