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MetabolomicsUPLC-QTOF-MS-Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis
Identification of new biomarkers may help in the early diagnosis of inflammatory bowel disease (IBD). In this study, ultrahigh-performance liquid chromatography equipped with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS) was used to analyze the untargeted lipidomics and compare plasma l...
2021-10-18 | MTBLS1183 | MetaboLights
MetabolomicsSurvival of the littlest: Navigating sepsis diagnosis beyond inflammation in preterm neonates
Background Sepsis diagnosis in preterm neonates is challenging due to symptom overlap with non-infectious inflammatory conditions, and slow, unreliable diagnostic practices. This study aims to identify metabolic biomarkers to elucidate sepsis pathophysiology, and enable timely, accurate diagnosis, w...
2025-07-07 | MTBLS10665 | MetaboLights
ProteomicsProteomics and bioinformatics investigations to improve serological diagnosis of canine brucellosis
Brucella canis is pathogenic for dogs and humans. Serological diagnosis is a cost-effective approach for disease surveillance, but a major drawback of current serological tests is the cross-reactivity with other bacteria that results in false positive reactions, and development of indirect tests wit...
ORGANISM(S): Brucella canis ATCC 23365 
2023-10-24 | PXD042682 | Pride
Brucella canis  western blotting  mass spectrometry  protein identification Bioinformatics 
GenomicsSerological microRNAs as biomarkers for the diagnosis of adolescent tuberculosis infection in pleura
Serological microRNAs as biomarkers for the diagnosis of adolescent tuberculosis infection in pleura
PRJNA745165 | ENA
TranscriptomicsRefining brucellosis diagnosis by blood transcriptional profiling
Diagnosis of brucellosis remains challenging for several reasons, including lack of culture sensitivity, nonspecific symptomatology, and high prevalence of positive serology in endemic areas. The main objectives of this study were to identify blood biomarkers specific to brucellosis compared to othe...
ORGANISM(S): Homo sapiens 
2015-06-06 | E-GEOD-69597 | biostudies-arrayexpress
ClinicalEvaluation of novel serological markers for early diagnosis of colorectal neoplasia
Interventions: Group 1: Observational study: Participants in the colorectal cancer screening program, who undergo colonoscopy and a serological examination. Primary outcome(s): sensitivity and specificity of the three serological tests at predefined cutpoints with colonoscopy as gold standard for as...
2429165 | ecrin-mdr-crc
UnknownEvaluation of Three Serological Tests for Diagnosis of Canine Brucellosis.
Not available
S-EPMC10536495 | biostudies-literature
GenomicsMolecular and serological diagnosis of multiple bacterial zoonoses in febrile outpatients in Garissa County, north-eastern Kenya
Molecular diagnosis of febrile patients in Kenya
PRJEB65963 | ENA
ProteomicsComparative Proteomics between Brucella abortus 2308 and Genetically Marked Vaccine A19ΔvirB12 Reveal Attenuation Mechanism and Supplementary Differential Diagnosis Antigens
Brucella abortus is an important zoonotic pathogen that causes severe economic loss to husbandry and poses a threat to human health. The B. abortus A19 live vaccine has been extensively used to prevent bovine brucellosis in China. However, A19 has the limitation of diagnosis interference and residua...
ORGANISM(S): Brucella abortus (strain 2308) 
2021-09-09 | PXD022031 | Pride
B. abortus  a19δvirb12  proteomics  differential diagnosis  attenuation mechanism 
OtherDiscovery of melanotransferrin as a serological marker of colorectal cancer by secretome analysis and quantitative proteomics.
Data from PeptideAtlas, [[http://www.peptideatlas.org/PASS/PASS00565 PASS00565]]. File: 100521_HCT-116_OG11.mzml. Published as part of . From the Abstract: {{i}} In order to discover serological colorectal cancer (CRC) markers, we analyzed cell line secretome to gather proteins of higher potential ...
ORGANISM(S): Homo_sapiens_viruses, Cow,human 
GPM11210029831 | GPMDB
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