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MetabolomicsEpithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic
Immunity to intestinal helminth infections has been well studied, but the mechanism of helminth killing prior to expulsion remains unclear. Here we identify epithelial-cell-derived phospholipase A2 group 1B (PLA2g1B) as a host-derived endogenous anthelmintic. PLA2g1B is elevated in resistant mice an...
2018-08-13 | MTBLS523 | MetaboLights
TranscriptomicsDistinct and sexually dimorphic X dosage compensation states in the mammalian germline
This experiment depicts RNA-Seq datasets from wild type XY male and XX female, as well as sex chromosomally abnormal XO female (Turner syndrome) and XX male (Klinefelter variant syndrome) mouse germ cells before, during and after germline reprogramming. This range from E6.5 epiblasts, fluorescence a...
ORGANISM(S): Mus musculus 
2017-02-06 | E-MTAB-4616 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hippocampus from wild type and ZIF268(Egr1) knock-out mice subjected to kainic acid induced seizures
ZIF268(Egr1) KO mice and wild type littermate subjected KA induced seizure and the hippocampus subregion isolated 2hrs later
ORGANISM(S): Mus musculus 
2008-12-29 | E-MEXP-1483 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of expressed human chromosome 21 genes in transchromosomic mouse embryos carrying a freely segregating copy of Hsa21
Detection of expressed human chromosome 21 genes in transchromosomic mouse embryos carrying a freely segregating copy of Hsa21.
ORGANISM(S): Mus musculus 
2005-11-19 | E-MEXP-409 | biostudies-arrayexpress
TranscriptomicsHigh-resolution analysis of gene activity during the Xenopus mid-blastula transition
The Xenopus mid-blastula transition (MBT) marks the onset of large-scale zygotic transcription, as well as an increase in cell cycle length and a loss of synchronous cell divisions. Little is known about what triggers the activation of transcription or how newly expressed genes interact with each ot...
ORGANISM(S): Xenopus (Silurana) tropicalis 
2014-03-27 | E-GEOD-56242 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of Lgr6 positive and negative cells in mouse mammary gland
Lgr6-positive cells have been shown to label stem/progenitors cells in several tissues including tongue and skin. However their role in mammary gland has never been investigated. Here we used Lgr6-eGFP-IRES-CreER2 mice to isolate and characterize Lgr6-positive population in mammary gland of 5-week o...
ORGANISM(S): Mus musculus 
2016-09-06 | E-GEOD-75648 | biostudies-arrayexpress
UnknownEffects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial.
Not available
S-EPMC6336936 | biostudies-literature
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