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ProteomicsIntrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors
G protein-coupled receptors (GPCRs) are typically characterized by their seven transmembrane (7TM) architecture, and interaction with two universal signal-transducers namely, the heterotrimeric G-proteins and β-arrestins (βarrs). Synthetic ligands and receptor mutants have been designed to elicit tr...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD027887 | Pride
Gpcr kinases Gpcrs Β-arrestins Complement c5a Biased signaling Β-arrestin-coupled receptors Seven transmembrane receptors 
UnknownQuantifying ligand bias at seven-transmembrane receptors.
Not available
S-EPMC3164332 | biostudies-literature
UnknownIntrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors.
Not available
S-EPMC7612807 | biostudies-literature
UnknownHeterotrimeric G protein signaling outside the realm of seven transmembrane domain receptors.
Not available
S-EPMC2912057 | biostudies-literature
UnknownTwo orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection.
Not available
S-EPMC2198994 | biostudies-literature
UnknownMolecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors.
Not available
S-EPMC7615931 | biostudies-literature
UnknownMining the Arabidopsis thaliana genome for highly-divergent seven transmembrane receptors.
Not available
S-EPMC1794564 | biostudies-literature
UnknownMathematical models for quantitative assessment of bioluminescence resonance energy transfer: application to seven transmembrane receptors oligomerization.
Not available
S-EPMC3428587 | biostudies-literature
UnknownMammalian α arrestins link activated seven transmembrane receptors to Nedd4 family e3 ubiquitin ligases and interact with β arrestins.
Not available
S-EPMC3517545 | biostudies-literature
UnknownSeven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.
Not available
S-EPMC2879912 | biostudies-literature
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