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MetabolomicsTargeted plasma metabolomics combined with machine learning for the diagnosis of acute SARS-CoV-2

The routine clinical diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is largely restricted to real-time reverse transcription polymerase chain reaction (RT-qPCR), and tests that detect SARS-CoV-2 nucleocapsid antigen. Given the diagnostic delay and suboptimal sensitivity...

2024-08-26 | MTBLS6739 | MetaboLights
TranscriptomicsHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Severe acute respiratory syndrome coronavirus (SARS-CoV) causes a respiratory disease leading to death in 10% of the infected people. A mouse adapted SARS-CoV lacking the envelope (E) protein (rSARS-CoV-MA15-?E) is attenuated in vivo. To identify E protein domains and host responses that contribute ...
ORGANISM(S): Mus musculus 
2015-05-19 | E-GEOD-59185 | biostudies-arrayexpress
MetabolomicsImmunomodulatory fecal metabolites are associated with mortality in COVID-19 patients with respiratory failure
Respiratory failure and mortality from COVID-19 result from virus- and inflammation-induced lung tissue damage. The intestinal microbiome and associated metabolites are implicated in immune responses to respiratory viral infections, however their impact on progression of severe COVID-19 remains uncl...
2023-05-02 | MTBLS5288 | MetaboLights
GenomicsSevere acute respiratory syndrome coronavirus 2
Severe acute respiratory syndrome coronavirus 2 Genome sequencing
PRJNA634396 | ENA
GenomicsSevere acute respiratory syndrome coronavirus 2
Severe acute respiratory syndrome coronavirus 2 Genome sequencing
PRJNA796972 | ENA
GenomicsSevere acute respiratory syndrome coronavirus 2
Severe acute respiratory syndrome coronavirus 2 Genome sequencing
PRJNA765540 | ENA
GenomicsSevere acute respiratory syndrome coronavirus 2
Severe acute respiratory syndrome coronavirus 2 Genome sequencing
PRJNA896579 | ENA
GenomicsSevere acute respiratory syndrome coronavirus 2
Severe acute respiratory syndrome coronavirus 2 Raw sequence reads
PRJNA717113 | ENA
GenomicsSevere acute respiratory syndrome coronavirus 2
Severe acute respiratory syndrome coronavirus 2 Genome sequencing and assembly
PRJNA723527 | ENA
TranscriptomicsTranscription profiling of blood samples from human patients with severe acute respiratory syndrome (SARS)
To understand the host response to this pathogen, we investigated the gene expression profiles of peripheral blood mononuclear cells (PBMCs) derived from SARS patients, and compared with healthy controls.
ORGANISM(S): Homo sapiens 
2007-08-04 | E-GEOD-1739 | biostudies-arrayexpress
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