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MetabolomicsSex-specific metabolic shifts in plasma of COVID-19 patients after cure
Metabolic profiling in COVID-19 patients has been associated with disease severity, but there is no report on sex-specific metabolic changes in discharged survivors. Herein we used an integrated approach of LC-MS-and GC-MS-based untargeted metabolomics to analyze plasma metabolic characteristics in ...
2022-01-10 | MTBLS2224 | MetaboLights
MetabolomicsSex-specific effects of CD248 on metabolism and the adipose tissue lipidome

Cd248 has recently been associated with adipose tissue physiology, demonstrated by reduced weight gain in high fat diet-fed mice with genetic deletion of Cd248 relative to controls. Here we set out to determine the metabolic consequences of loss of Cd248. Strikingly, we find these to be sex speci...

2023-01-05 | MTBLS6615 | MetaboLights
MetabolomicsAnalysis of sex-specific lipid metabolism of Plasmodium falciparum points to the importance of sphingomyelin for gametocytogenesis
Male and female Plasmodium falciparum gametocytes are the parasite lifecycle stage responsible for transmission of malaria from the human host to the mosquito vector. Not only are gametocytes able to survive in radically different host environments, but they are also precursors for male and female g...
2022-04-05 | MTBLS4137 | MetaboLights
MetabolomicsKynurenic acid underlies sex-specific immune responses to COVID-19
Sex-related differences in Coronavirus Disease (COVID-19) severity and mortality exist, with the male sex being a potential risk factor1. It was recently shown that patients with mild to moderate SARS-CoV-2 infection have elevated levels of inflammatory cytokines and chemokines, and sex-differences ...
2020-09-08 | MTBLS1987 | MetaboLights
MetabolomicsBiotransformation causes the sex-specific regulation of polychlorinated biphenyls during metamorphosis of silkworm (Bombyx mori) and their effect on the silkworm development

The decline in insect populations is indisputable. Currently, the effects of persistent organic pollutants on insect populations have not been sufficiently investigated. Maternal transfer of pollutants is considered to be an inherently correct reason for sex differences in pollutant le...

2025-09-09 | MTBLS12906 | MetaboLights
MetabolomicsHaplotype-resolved female and male genomes reveal sex-specific genomic regions and provide insights into thermal stress in Scapharca subcrenata

Integrated analyses of transcriptomic, proteomic and metabolomic data sets consistently highlights the crucial involvement of protein function and retinol metabolism pathways in the heat-resistant strain of S. subcrenata. These findings underscore the significance of these pathways in e...

2024-11-11 | MTBLS11038 | MetaboLights
MetabolomicsMetabolic profiling at COVID-19 onset shows disease severity and sex-specific dysregulation
Not available
ORGANISM(S): Homo sapiens 
ST002194 | MetabolomicsWorkbench
MetabolomicsCore Functional Nodes and Sex-Specific Pathways in Human Ischemic and Dilated Cardiomyopathy
Not available
ORGANISM(S): Homo sapiens 
ST001364 | MetabolomicsWorkbench
GenomicsUnbiased, Genome-wide in vivo Mapping of Transcriptional Regulatory Elements Reveals Sex Differences in Chromatin Structure Associated with Sex-specific Liver Gene Expression
We have used a simple and efficient method to identify condition-specific transcriptional regulatory sites in vivo to help elucidate the molecular basis of sex-differences in transcription, which are widespread in mammalian tissues and affect normal physiology, drug response, inflammation and diseas...
ORGANISM(S): Mus musculus 
2010-09-28 | E-GEOD-21777 | biostudies-arrayexpress
MetabolomicsMetabolomics of lung microdissections reveals region- and sex-specific metabolic effects of acute naphthalene exposure in mice (part II)
Not available
ORGANISM(S): Mus musculus 
ST001841 | MetabolomicsWorkbench
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