Sexual differentiation

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Unknown (1325)
Transcriptomics (1068)
Genomics (416)
Proteomics (29)
Methylation profiling (4)
Metabolomics (2)
Models (1)
Genomic (1)
Other (1)

Organisms

Mus musculus (409)
Homo sapiens (357)
Rattus norvegicus (33)
Plasmodium falciparum (32)
Schizosaccharomyces pombe (28)
Gallus gallus (25)
Arabidopsis thaliana (21)
Caenorhabditis elegans (21)
Drosophila melanogaster (20)
Danio rerio (17)
Sus scrofa (12)
Saccharomyces cerevisiae (7)
Bos taurus (6)
Carassius auratus (5)
Ovis aries (5)
Anopheles gambiae (4)
Oncorhynchus mykiss (4)
Oryzias latipes (4)
Plasmodium falciparum 3D7 (4)
Macaca mulatta (3)
Xenopus laevis (3)
Etheostoma caeruleum (2)
Populus tremula x Populus tremuloides (2)
Mycolicibacterium smegmatis MC2 155 (2)
Cereibacter sphaeroides (1)
Botryllus schlosseri (1)
Nostoc punctiforme (1)
Ericerus pela (1)
Oreochromis niloticus (1)
Chelon labrosus (1)

Organisms

Mus musculus (79)
Plasmodium falciparum (24)
Schizosaccharomyces pombe (13)
Danio rerio (9)
Drosophila melanogaster (8)
Homo sapiens (8)
Gallus gallus (6)
Chlamydomonas reinhardtii (5)
Cryptococcus neoformans H99 (4)
Caenorhabditis elegans (3)
Oryzias latipes (3)
Toxoplasma gondii (3)
Plasmodium falciparum NF54 (2)
Plasmodium yoelii yoelii (2)
Cryptococcus deneoformans (2)
Plasmodium falciparum 3D7 (2)
Cryptococcus neoformans (2)
Fusarium graminearum (2)
Ruditapes philippinarum (2)
Schmidtea mediterranea (2)
Macrobrachium rosenbergii (2)
Gasterosteus aculeatus (2)
Sus scrofa (2)
Bos taurus (2)
Boechera holboellii/Boechera stricta mixed EST library (1)
Pipilo sp. (1)
Pinctada margaritifera (1)
Cryptococcus deneoformans XL280 (1)
Coccinia grandis (1)
Pistacia chinensis (1)

Repository

biostudies-arrayexpress (911)
ENA (358)
geo (215)
pride (15)
iProX (7)
EVA (4)
jPOST (4)
EGA (2)
MetaboLights (2)
ExpressionAtlas (1)
Cell Collective (1)
dbGaP (1)
MassIVE (1)
PAXDB (1)

Tissue

Brain (2)
Blood (1)
Blood cell (1)
Cell culture (1)
Cell suspension culture (1)
Flower bud (1)
Monocyte (1)
Plant cell (1)
Primordial germ cell (1)
Tachyzoite (1)
Zygote (1)

Disease

Normal (5)
Monoclonal gammopathy of undetermined significance (MGUS) (1)
Inflammatory bowel disease (1)
Microscopic Polyangiitis (1)
Uninfected 11dpi (1)
Asthma (1)
Infertility (1)
Malaria (1)

Technology Type

Mass Spectrometry (15)
Bottom-up proteomics (6)
Shotgun proteomics (4)
Data-dependent acquisition (2)
Data-independent acquisition (2)
Mass spectrometry assay (1)
Mass spectrometry (1)
Affinity purification coupled with mass spectrometry proteomics (1)
Gel-based experiment (1)
HDMSE (1)
Proteogenomics (1)
Top-down proteomics (1)

Instrument Platform

NextSeq 550 (8)
Illumina NovaSeq 6000 (4)
NextSeq 500 (4)
Illumina HiSeq 2500 (3)
Illumina HiSeq 4000 (3)
- (3)
Chromium 10x (2)
NextSeq 2000 (2)
NEBNext Ultra II Directional RNA Library Prep Kit (1)
RNeasy Plant Mini Kit (Qiagen, Hilden, Germany) (1)
The TLDA cards were analyzed on the Applied Biosystems 7900HT Real-Time PCR System. (1)
454 GS FLX+ (1)
GeneChip Scanner 3000 7G (1)
Axon GenePix 4000B scanning hardware (1)
Affymetrix Mouse Transcriptome Array 1.0 (1)
DNBSEQ-G400 (1)
BGISEQ-500 (1)
ABI 3500 Genetic Analyzer (1)
Liquid Chromatography MS - negative - hilic (1)
Liquid Chromatography MS - positive - hilic (1)
Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - negative - reverse phase (1)

Publication Date

2010 (155)
2013 (132)
2014 (117)
2011 (116)
2012 (115)
2015 (97)
2009 (76)
2025 (46)
2016 (45)
2008 (37)
2024 (29)
2022 (28)
2007 (25)
2026 (23)
2021 (23)
2019 (17)
2020 (15)
2017 (15)
2018 (14)
2023 (13)
2006 (12)
2005 (6)
2004 (3)
2002 (2)

UNIPROT ID/AC

5811.TGME49_002070 (1)
5811.TGME49_002130 (1)
5811.TGME49_002690 (1)
5811.TGME49_003210 (1)
5811.TGME49_003530 (1)
5811.TGME49_004050 (1)
5811.TGME49_004530 (1)
5811.TGME49_005130 (1)
5811.TGME49_005250 (1)
5811.TGME49_008350 (1)
5811.TGME49_008590 (1)
5811.TGME49_008730 (1)
5811.TGME49_009060 (1)
5811.TGME49_009100 (1)
5811.TGME49_009760 (1)
5811.TGME49_009870 (1)
5811.TGME49_012150 (1)
5811.TGME49_012890 (1)
5811.TGME49_013790 (1)
5811.TGME49_014080 (1)
5811.TGME49_014620 (1)
5811.TGME49_014950 (1)
5811.TGME49_015420 (1)
5811.TGME49_015710 (1)
5811.TGME49_015780 (1)
5811.TGME49_018260 (1)
5811.TGME49_018530 (1)
5811.TGME49_018830 (1)
5811.TGME49_019440 (1)
5811.TGME49_019860 (1)

CHEBI ID

CHEBI:177116 (1)
CHEBI:47495 (1)
CHEBI:177119 (1)
CHEBI:168018 (1)
CHEBI:177115 (1)
CHEBI:72727 (1)
CHEBI:10352 (1)
CHEBI:177123 (1)
CHEBI:177108 (1)
CHEBI:177106 (1)
CHEBI:177096 (1)
CHEBI:156165 (1)
CHEBI:175522 (1)
CHEBI:177107 (1)
CHEBI:131667 (1)
CHEBI:165771 (1)
CHEBI:177105 (1)
CHEBI:177095 (1)
CHEBI:177094 (1)
CHEBI:35812 (1)
CHEBI:8927 (1)
CHEBI:94521 (1)
CHEBI:166646 (1)
CHEBI:177110 (1)
CHEBI:177112 (1)
CHEBI:177092 (1)
CHEBI:177118 (1)
CHEBI:177122 (1)
CHEBI:168988 (1)
CHEBI:143585 (1)

Metabolite Name

[2-(5,7-dihydroxy-4-oxo-2-phenyl-3,4-dihydro-2H-1-benzopyran-8-yl)-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxidanesulfonic acid (1)
H-89 (1)
PHENYL-gamma-Aminobutyric Acid (1)
DIHYDROROTENONE (1)
3-carboxy-4-methyl-5-(4-hydroxypentyl)-2-furanpropanoic acid (1)
9-PAHSA (1)
1-(s-glutathionyl)-2,4-dinitrobenzene (1)
Myristic Acid ethyl ester (1)
Clopamide (1)
Palmitoleic Acid ethyl ester (1)
13-HpODE (1)
Stearic Acid ethyl ester (1)
Phytomonic Acid (1)
2-(Methylthio)ethanol (1)
Cyanidin 3-(2G-xylosylrutinoside) (1)
4-hydroxy Nonenal Glutathione (1)
4-hydroxy-butyric acid (1)
7Z, 10Z, 13Z, 16Z, 19Z-docosapentaenoic acid (1)
9-HpODE (1)
Glutamylmethionine (1)
Ethylene glycol distearate (1)
Toxin T2 tetrol (1)
Propyl 1-(propylsulfinyl)propyl disulfide (1)
Ganoderal A (1)
[3-[1-Formyl-2-(2-furanyl)ethenyl]]-2-(2-furanyl)-5-(2-furanylmethylene)-4,5-dihydro-a-methyl-4-oxo-1H-pyrrole-1-acetic acid, 9CI (1)
Androsterone sulfate (1)
DOPA sulfate (1)
S-Propyl 1-propanesulfinothioate (1)
DG(15:0/15:0/0:0) (1)
Glucoraphanin (1)

First Public Date

2014 (44)
2025 (42)
2022 (39)
2024 (37)
2020 (37)
2026 (31)
2023 (25)
2021 (24)
2019 (19)
2017 (16)
2018 (14)
2016 (10)
2013 (10)
2015 (9)
2010 (1)

Classification

protozoa (35)
fungi (14)

Modification

N6 (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (739)
RNA-seq of coding RNA (33)
Transcription profiling by RT-PCR (32)
Other (19)
Transcription profiling by tiling array (13)
Methylation profiling by array (12)
ChIP-seq (10)
MicroRNA profiling by array (10)
Unknown experiment type (8)
Comparative genomic hybridization by array (5)
ChIP-chip by array (4)
RNA-seq of non coding RNA (4)
Methylation profiling by high throughput sequencing (3)
RNA-seq of total RNA (3)
Transcription profiling by SAGE (1)
ChIP-chip by tiling array (1)
Animal - Single-cell sequencing (1)
Human - High-throughput sequencing (1)
Plant - One-color microarray (1)
Human - One-color microarray (1)
Animal - High-throughput sequencing (1)
RNAi profiling by array (1)
Bisulfite-seq (1)
ATAC-seq (1)
Ribo-seq (1)
ScATAC-seq (1)
Single nucleus RNA sequencing (1)
DNA-seq (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2010 (180)
2013 (173)
2014 (170)
2011 (147)
2012 (143)
2015 (139)
2022 (130)
2023 (122)
2025 (111)
2021 (110)
2016 (105)
2024 (97)
2019 (94)
2009 (91)
2020 (87)
2017 (80)
2018 (74)
2008 (52)
2007 (45)
2006 (23)
2026 (16)
2005 (15)
2002 (9)
2004 (6)
1999 (4)
2003 (3)
2001 (2)
2000 (2)
1998 (2)
1992 (1)

Lab affiliation

Department of Biochemistry & Molecular Biology, Michael Smith Laboratories, University of British Columbia, 2125 East Mall, Vancouver, British Columbia, Canada V6T 1Z4 (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY, 10461, USA (1)
Department of Chemistry, Michigan State University, 578 S Shaw Lane, East Lansing, Michigan 48824, USA (1)
Department of Molecular and Cellular Biology (MOCEL), University of Geneva, (Previously) Department of Fundamental Microbiology (DMF), University of Lausanne (1)
Department of Psychiatry, Seaver Autism Center for Research and Treatment, Mindich Child Health and Development Institute, Friedman Brain Institute, Alper Center for Neural Development and Regeneration, Icahn School of Medicine at Mount Sinai, USA (1)
Dept. of Molecular and Cellular Biology University of Geneva Quai Ernest-Ansermet 30 1211 Geneva 4 (1)
Faculty of Medicine & Health Sciences School of Life Sciences University of Nottingham Queen's Medical Centre Nottingham NG7 2UH UK (1)
INRAE Val de Loire France (1)
Laboratório de Melhoramento Genético Vegetal, Centro de Ciências e Tecnologias Agropecuárias (CCTA), Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Av. Alberto Lamego, Campos dos Goytacazes, RJ, Brazil. (1)
Proteomics platform Necker, Université de Paris - Structure Fédérative de Recherche Necker, INSERM US24/CNRS UMS3633, Paris, France (1)
School of Life Science, Queen's Medical Centre, University of Nottingham (1)
School of Life Sciences Queen's Medical Centre Nottingham NG7 2UH UK (1)
Shanghai Ocean University (1)
State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China (1)
ZBS6: Proteomics and Spectroscopy, Robert Koch-Institute (1)

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Transcription profiling of fission yeasts over-expressing transcription factors controlling sexual differentiation

Changes in gene expression are hallmarks of cellular differentiation. Sexual differentiation in fission yeast (Schizosaccharomyces pombe) provides a model system for gene expression programs accompanying and driving cellular specialization. The expression of hundreds of genes is modulated in succe...

ORGANISM(S): Schizosaccharomyces pombe

2008-01-01 | E-TABM-299 | biostudies-arrayexpress

Transcription profiling of fission yeast with deletion or overexpression of ste11 and changes in gene expression after nitrogen starvation of h plus, h minus, h90fus1 and h90ste11 cells to investigate control of gene expression during early sexual differentiation

Fission yeast cells belong to one of two specialized cell types, M or P. Specific environmental conditions trigger sexual differentiation, which leads to an internal program starting with pheromone signalling between M and P cells, followed by mating, meiosis and sporulation. The initial steps of ...

ORGANISM(S): Schizosaccharomyces pombe

2006-09-22 | E-TABM-139 | biostudies-arrayexpress

Sexual cell fate reprogramming in the ovary by DMRT1

Transcription factors related to the insect sex determination gene Doublesex (DMRT proteins) control sex determination and/or sexual differentiation in diverse metazoans. They also are implicated in transitions between sex-determining mechanisms during vertebrate evolution. In mice Dmrt1 is required...

ORGANISM(S): Mus musculus

2015-02-27 | E-GEOD-64960 | biostudies-arrayexpress

PRC1 coordinates timing of sexual differentiation of female primordial germ cells

In mammals, sex differentiation of primordial germ cells (PGCs) is determined by extrinsic cues from the environment1. In female PGCs, expression of Stimulated by retinoic acid 8 (Stra8) and meiosis are induced in response to retinoic acid (RA) provided by the mesonephroi2-4. Given the widespread ro...

ORGANISM(S): Mus musculus

2013-03-14 | E-GEOD-42782 | biostudies-arrayexpress

PRC1 coordinates timing of sexual differentiation of female primordial germ cells (RNA-Seq)

ORGANISM(S): Mus musculus

2013-03-14 | E-GEOD-42852 | biostudies-arrayexpress

Sexual dimorphism in osteogenic differentiation

PRJNA768873 | ENA

miRNA profiling in male and female chicken embryonic gonads during sexual differentiation

MicroRNAs (miRNAs) are a highly conserved class of small RNAs which function in a sequence-specific manner to post-transcriptionally regulate expression of target genes. Tissue-specific miRNA expression studies have discovered numerous functions for miRNAs in various aspects of embryonic developmen...

ORGANISM(S): Gallus gallus

2010-05-18 | E-GEOD-13154 | biostudies-arrayexpress

Identification of a subtelomeric gene family expressed during the asexual-sexual stage transition in Plasmodium falciparum

For malaria transmission, the parasite must undergo sexual differentiation into mature gametocytes. However, the molecular basis for this critical transition in the parasites life cycle is unknown. Six previously uncharacterized genes, Pfg14.744, Pfg14.745, Pfg14.748, Pfg14.763, Pfg14.752 and Pfg6.6...

ORGANISM(S): Plasmodium falciparum

2014-10-16 | E-GEOD-62364 | biostudies-arrayexpress

Transcription profiling of fission yeast SAGA mutants shows that the SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8

The SAGA complex is a conserved multifunctional coactivator known to play broad roles in eukaryotic transcription. To gain new insights into its functions, we have performed biochemical and genetic analyses of SAGA in the fission yeast, Schizosaccharomyces pombe. Purification of the S. pombe SAGA ...

ORGANISM(S): Schizosaccharomyces pombe

2008-11-19 | E-MTAB-53 | biostudies-arrayexpress

Transcription profiling of fission yeast sexual differentiation

Not available

ORGANISM(S): Schizosaccharomyces pombe

2002-08-05 | E-SNGR-2 | biostudies-arrayexpress

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