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TranscriptomicsE12.5 Murine lateral cortical progenitor cells: Pax6sey/sey vs. Pax6+/+
The mechanisms by which the early spatiotemporal expression patterns of transcription factors such as Pax6 regulate the region-specific proliferation rates of neural progenitors are poorly understood. Pax6 is expressed in a gradient across the developing cortex and is essential for normal corticogen...
ORGANISM(S): Mus musculus 
2013-01-31 | E-GEOD-38703 | biostudies-arrayexpress
TranscriptomicsMouse cornea trasnciptomics: Pax6-sey mutation (Aniridia model) and Duloxetine administration - Affymetrix GeneChip Mouse Gene 2.0 ST Array (MoGene-2_0-st) in -
Cornea transcriptomic analysis in a mouse model of slowly progressing aniridia-associated keratopathy (AAK) the heterozygous 129S1.Cg-Pax6Sey/Mmmh strain on the 129S1/SvImJ background (MMRRC stock #050624-MU)(4, 5). The Pax6 mutation of this model is a spontaneous point mutation in exon 8 of the Pax...
ORGANISM(S): Mus musculus 
2026-01-30 | E-MTAB-16492 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat wild type and Pax6 mutant hindbrain and forebrain samples
Pax6 is a transcription factor that is expressed in neuroepithelial cells from the initial stage of brain development. Region specific expression of Pax6 plays pivotal roles in the developing CNS, including brain patterning, neuronal specification, neuronal migration, and axonal projection. Regard...
ORGANISM(S): Rattus norvegicus 
2007-10-08 | E-GEOD-2272 | biostudies-arrayexpress
TranscriptomicsFunctional dissection of the Paired domain of Pax6 – distinct roles of subdomains in neurogenesis and proliferation
The transcription factor Pax6 acts as a key developmental regulator in various organs. In the developing brain Pax6 regulates patterning, neurogenesis and proliferation, but how these diverse effects are mediated at the molecular level is not well understood. As Pax6 regulates forebrain development ...
ORGANISM(S): Mus musculus 
2013-03-19 | E-GEOD-35260 | biostudies-arrayexpress
UnknownEnhanced Antioxidative Capacity Transfer between Sow and Fetus via the Gut-Placenta Axis with Dietary Selenium Yeast and Glycerol Monolaurate Supplementation during Pregnancy.
Not available
S-EPMC10886224 | biostudies-literature
UnknownThe Selenium Yeast vs Selenium Methionine on Cell Viability, Selenoprotein Profile and Redox Status via JNK/ P38 Pathway in Porcine Mammary Epithelial Cells.
Not available
S-EPMC9011133 | biostudies-literature
TranscriptomicsHT-SELEX of recombinant C2H2 zinc finger domains of Sall4
To define the sequence preference of SALL4 C2H2 zinc finger domains, we performed SELEX coupled with high-throughput sequencing (HT-SELEX) using the purified SALL4 ZFC1, ZFC2 and ZFC4 domains combined with no protein control experiment.
ORGANISM(S): artificial sequences 
2021-01-05 | E-MTAB-9236 | biostudies-arrayexpress
UnknownUltrasound-assisted extraction of highly nutritious date sugar from date palm (Phoenix dactylifera) fruit powder: Parametric optimization and kinetic modeling.
Not available
S-EPMC9356216 | biostudies-literature
TranscriptomicsRegulation of Tlx3 by Pax6 is required for the restricted expression of Chrnα3 in Cerebellar Granule Neuron progenitors during development
Homeobox gene Tlx3 is known to promote glutamatergic differentiation and is expressed in post-mitotic neurons of CNS. Contrary to this here, we discovered that Tlx3 is expressed in the proliferating progenitors of the external granule layer in the cerebellum, and examined factors that regulate this...
ORGANISM(S): Mus musculus 
2016-06-30 | E-GEOD-82097 | biostudies-arrayexpress
TranscriptomicsRNA-Seq analysis of E15.5 mouse Insm1, Neurod1 and Pax6 knockouts vs Insm1GFP.Cre/+ controls
This experiment used RNA-Seq technology to explore gene expression in mouse Insm1GFP.Cre/+ controls and Insm1 (Insm1GFP.Cre/GFP.Cre), Neurod1 (Insm1GFP.Cre/+; Neurod1LacZ/LacZ), or Pax6 (Insm1GFP.Cre/+; Pax6fl/fl) knockout FACS sorted pancreatic endocrine cells at E15.5. Comparison of Insm1GFP.Cre+/...
ORGANISM(S): Mus musculus 
2021-08-23 | E-MTAB-10262 | biostudies-arrayexpress
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