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The PD-1/PD-L1 axis represents a cornerstone of cancer immunotherapy, yet the dynamic shuttling of PD-L1 between endosomal recycling and lysosomal degradation routes limits durable responses. Using a CRISPR screen targeting glycosphingolipid metabolism, we identify TM9SF2 as a key regulator of PD...

2026-02-05 | MTBLS13838 | MetaboLights
This dataset is to provide a transcriptional status reference for the Sf9 cell line, used for ChIP assays
ORGANISM(S): Spodoptera frugiperda 
Spodoptera frugiperda is a notorious agricultural pest in its caterpillar form. As most Lepidoptera, its genome is organized in 31 chromosomes with dispersed centromeres instead of a single one per chromosome. This property is called holocentrism and is found in several animal groups as well as some...
ORGANISM(S): Spodoptera frugiperda 
Whole transcriptome sequencing of the rhabodvirus-negative Sf9 cell clone 13F12
MicroRNAs (miRNAs) as small non-coding RNAs play important roles in many biological processes such as development, cell signalling and immune response. Studies also suggest that miRNAs are important in host–virus interactions where the host limits virus infection by differentially expressing miRNAs ...
ORGANISM(S): Spodoptera frugiperda 
published at http://dx.plos.org/10.1371/journal.pone.0025708 Effect of hormone agonists on Sf9 cells : methoxyfenozide (Mtfz) and methoprene (Mtp) We have 12 microarrays corresponding to 6 dye swaps , there is 3 biological replicates for each comparison. 6 microarrays: dye swap of 3 biological repl...
ORGANISM(S): Spodoptera frugiperda 
Spodoptera frugiperda isolate:Sf9 Genome sequencing and assembly
Effect of phenobarbital on Sf9 cell cultures genes expression. RNA from phenobarbital treated Sf9 cell cultures were compared to control treated (DMSO) Sf9 cell
ORGANISM(S): Spodoptera frugiperda 
2018-09-22 | GSE32337 | GEO
Effect of 8 compounds (xanthotoxine, fipronil, clofibrate, 2tridecanone, indole3carbinol, indole, quercitine, deltamethrine) on Sf9 cell cultures genes expression. RNA from treated Sf9 cell cultures were compared to control treated (DMSO) Sf9 cell.
ORGANISM(S): Spodoptera frugiperda 
2018-09-22 | GSE32336 | GEO
RNA-seq of Spodoptera frugiperda Sf9 cell line
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