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Here we used DNA microarrays to identify hyperadenylated transcripts detected in pab2 cells. Using this genome-wide approach, we found that the absence of Pab2 leads to the accumulation of polyadenylated snoRNAs and we describe the molecular mechanism of their accumulation.
ORGANISM(S): Schizosaccharomyces pombe 
Molecular classification of cancer has entered clinical routine to inform diagnosis, prognosis and treatment decisions. At the same time, new tumor entities have been identified that cannot be defined histologically. For central nervous systems tumors, the current World Health Organization classific...
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