Sort   by:  
 Page size 
MetabolomicsAge-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.

The incidence of intestinal diseases increases with age, but the regulators of gut aging and the molecules linking gut aging and diseases remain largely unknown. By profiling the transcriptome, proteome, phosphoproteome and metabolome of 104 Macaca fascicularis large intestinal tissues, ...

2023-12-14 | MTBLS7612 | MetaboLights
UnknownTgfb3 and Mmp13 regulated the initiation of liver fibrosis progression as dynamic network biomarkers.
Not available
S-EPMC7812286 | biostudies-literature
UnknownPrognostic value of SRSF2 mutations in patients with de novo myelodysplastic syndromes: A meta-analysis.
Not available
S-EPMC5617234 | biostudies-literature
UnknownSerotonin regulates maternal calcium homeostasis during the perinatal period of sheep.
Not available
S-EPMC6915205 | biostudies-literature
ProteomicsDeciphering the clinical significance and kinase functions of GSK3α in colon cancer by proteomics and phosphoproteomics
In this study, paired tumors and distant normal tissues (DNTs) collected from 78 treatment-naïve colon cancer patients were subjected to tandem mass tag (TMT)-based proteomics. We found that the expression of GSK3α, but not GSK3β, was significantly correlated with the overall survival (OS) of colon ...
ORGANISM(S): Homo Sapiens 
2023-03-03 | PXD038830 |
ProteomicsIntegrative omics reveals magnesium deficiency as a driver factor of colorectal cancer
Magnesium (Mg) deficiency is associated with increased risk and malignancy of colorectal cancer (CRC), but the underlying mechanisms remain elusive. In our study, we used genomic, proteomic, and phosphoproteomic data to reveal the effects of low Mg content on genomic instability and tumor metastasis...
ORGANISM(S): Homo Sapiens 
2023-06-05 | PXD042746 |
UnknownThe loss of SHMT2 mediates 5-fluorouracil chemoresistance in colorectal cancer by upregulating autophagy.
Not available
S-EPMC8195740 | biostudies-literature
UnknownPlasma concentration of malaria parasite-derived macrophage migration inhibitory factor in uncomplicated malaria patients correlates with parasitemia and disease severity.
Not available
S-EPMC2952996 | biostudies-literature
UnknownProteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype.
Not available
S-EPMC2656902 | biostudies-literature
MetabolomicsPRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis
PRDM family members are sequence-specific transcriptional regulators involved in cell identity and fate determination and are often dysregulated in cancer. The PRDM15 gene is of particular interest, given its relatively low expression in adult tissues and its overexpression in follicular lymphomas (...
2025-06-16 | MTBLS1639 | MetaboLights
Sort   by:  
 Page size