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ProteomicsEP3 deletion in macrophages aggravates diet-induced obesity in mice by suppressing SPARC
Macrophages are primary immune cells involved in obesity-triggered chronic low-grade inflammation in adipose tissues. Prostaglandin (PG) E2, mainly generated from macrophages, can regulate adipose tissue remodeling. Here, we observed that PGE2 receptor subtype 3 (EP3) was remarkably downregulated in...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-25 | PXD063443 | Pride
Macrophage Obesity Sparc E-prostanoid 3 receptor 
TranscriptomicsWhole gene expression data from osteocyte-like cell line MLO-Y4 under large gradient high magnetic field (LG-HMF)
osteocyte is the mechanosensor in bone, taking up pivotal position in mediating the mechano-induced bone remodeling. Dimagnetic levitation has been used to stimulating a reduced gravity environment for studing the effects of changed gravity to different organisms.we constructed a superconducting mag...
ORGANISM(S): Mus musculus 
2015-02-02 | E-GEOD-62128 | biostudies-arrayexpress
UnknownComparison of Measures to Predict Mortality and Length of Stay in Hospitalized Patients.
Not available
S-EPMC6488393 | biostudies-literature
UnknownInjectable Microporous Annealed Crescent-Shaped (MAC) Particle Hydrogel Scaffold for Enhanced Cell Infiltration.
Not available
S-EPMC11102933 | biostudies-literature
ProteomicsAn impaired respiratory electron chain triggers down-regulation of the energy metabolism and de-ubiquitination of solute carrier amino acid transporters
We integrated metabolome and proteome profiles of the parental cell line 143B.TK- versus ?0, including PTM analyses such as phosphorylation and ubiquitination to characterize the impact of the absence of mtDNA for the entire cell. For quantitative proteome profiling, we used a shotgun LC-MS/MS appro...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080873 | MassIVE
UnknownImproved Humoral Immunity and Protection against Influenza Virus Infection with a 3d Porous Biomaterial Vaccine.
Not available
S-EPMC10625058 | biostudies-literature
UnknownNegative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression.
Not available
S-EPMC7210294 | biostudies-literature
UnknownFDG PET/CT Imaging 1 Week after a Single Dose of Pembrolizumab Predicts Treatment Response in Patients with Advanced Melanoma.
Not available
S-EPMC11062839 | biostudies-literature
UnknownCopy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia.
Not available
S-EPMC2694973 | biostudies-literature
UnknownAzithromycin Protects against Zika virus Infection by Upregulating virus-induced Type I and III Interferon Responses.
Not available
S-EPMC6879226 | biostudies-literature
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