Sort   by:  
 Page size 
GenomicsBAZ1B in Nucleus Accumbens Regulates Reward-Related Behaviors in Response to Distinct Emotional Stimuli
ATP-dependent chromatin remodeling proteins are being implicated increasingly in the regulation of complex behaviors, including models of several psychiatric disorders. Here, we demonstrate that Baz1b, an accessory subunit of the ISWI family of chromatin remodeling complexes, is upregulated in the n...
ORGANISM(S): Mus musculus 
2016-07-30 | E-GEOD-85005 | biostudies-arrayexpress
GenomicsHistone Arginine Methylation in Cocaine Action: Essential Role of Src Signaling in the Nucleus Accumbens
Despite addiction being one of the most prevalent and debilitating disorders worldwide, effective treatments are lacking. Repeated cocaine exposure induces maladaptive transcriptional regulation within the brainâ??s reward circuitry, such as the nucleus accumbens (NAc), and epigenetic mechanisms, su...
ORGANISM(S): Mus musculus 
2016-08-08 | E-GEOD-85310 | biostudies-arrayexpress
Genomicsb-Catenin Mediates the Development of Behavioral Resilience [ChIP-Seq]
Here we show that ?-catenin mediates pro-resilient and anxiolytic effects in mice in the nucleus accumbens (NAc), a key brain reward region, an effect that is mediated by ?-catenin signaling in D2-type medium spiny neurons (MSNs) specifically. Conversely, blocking ?-catenin function in NAc promotes...
ORGANISM(S): Mus musculus 
2014-11-13 | E-GEOD-61294 | biostudies-arrayexpress
Sort   by:  
 Page size