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UnknownDataset of output impedances of current sources by analytical method and by experimental method.
Not available
S-EPMC6262198 | biostudies-literature
ProteomicsComparison of Different Mass-Spectrometry Workflows for the Proteomic Analysis of Tear Fluid
Proteomic analysis of tear fluid is challenging mainly due to a wide dynamic range of proteins and small sample volume. However, recent advancements in mass spectrometry have revolutionized the field of proteomics through its unprecedented depth, speed, and accuracy even with small sample volumes. I...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD030990 | Pride
Tear film  proteomics  biomarkers  dry eye disease  ocular surface  mass spectrometry 
ProteomicsThe Constitutive Proteome of Human Aqueous Humor
Aqueous humor (AH) is the fluid in the anterior and posterior chambers of the eye that contains proteins regulating ocular homeostasis. Analysis of aqueous humor proteome is challenging mainly due to low sample volume and protein concentration. In this study, by utilizing state of the art technology...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD022463 | Pride
Aqueous humor  mass spectrometry  proteomics 
ProteomicsAssociation of tear fluid glutathione synthetase and glutathione levels with amyloid positivity
Tear fluid is a promising source of biomarkers for Alzheimer’s disease (AD). This study characterized the tear fluid proteome across AD and dementia stages. Tear fluid was collected from 60 participants, cognitively normal (CN) individuals (n=32), patients with mild cognitive impairment (n=14), and ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-25 | PXD072063 | Pride
Tear fluid Amyloid pet Alzheimer’s disease Dementia Glutathione synthetase Diagnosis Proteomics Immunoassay Biomarkers 
ProteomicsTear Fluid Proteomics: A Comparative Study of DIA and DDA Mass Spectrometry
Background: Mass spectrometry is a powerful technique for tear fluid proteomics, offering critical insights into its complex molecular composition. Data-dependent acquisition (DDA), the most commonly used approach, preferentially selects high-abundance proteins, limiting reproducibility and the quan...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2025-10-20 | PXD062422 | Pride
Tear fluid  schirmer strip  proteomics  biomarkers  mass spectrometry 
ProteomicsTear Fluid Proteomics: A Comparative Study of DIA and DDA Mass Spectrometry
Background: Mass spectrometry is a powerful technique for tear fluid proteomics, offering critical insights into its complex molecular composition. Data-dependent acquisition (DDA), the most commonly used approach, preferentially selects high-abundance proteins, limiting reproducibility and the quan...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2025-10-20 | PXD062423 | Pride
Tear fluid  schirmer strip  proteomics  biomarkers  mass spectrometry 
ProteomicsSpecies-specific tear proteomic signatures in humans and rabbits: A DIA mass spectrometry comparative study
Purpose: Rabbits exhibit an exceptionally low blink frequency and a markedly prolonged tear breakup time compared with humans. These physiological differences suggest the presence of specialized tear-stabilizing mechanisms that may be reflected in the molecular composition of rabbit tear fluid. This...
ORGANISM(S): Homo sapiens (Human) Oryctolagus cuniculus (Rabbit) 
2026-09-25 | PXD072372 | Pride
UnknownDouble bubble pneumo-descemetopexy for the management of Descemet membrane detachment: An innovative technique.
Not available
S-EPMC10391505 | biostudies-literature
ProteomicsMass spectrometric detection of keratins in tear fluid
Keratin contamination is a common problem in mass spectrometry proteomic analyses, particularly in bottom-up mass spectrometry. The purpose of this study was to determine the protein contaminants introduced during the proteomic analysis of tear fluid.Human tear fluid samples were collected using Sch...
ORGANISM(S): Homo sapiens (Human) 
2025-03-03 | PXD061409 | Pride
Tear fluid Keratins Schirmer strip Mass spectrometry Proteomics Biomarkers 
UnknownSafety and Efficacy of Durvalumab (MEDI4736), an Anti-Programmed Cell Death Ligand-1 Immune Checkpoint Inhibitor, in Patients With Advanced Urothelial Bladder Cancer.
Not available
S-EPMC5569690 | biostudies-literature
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