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ProteomicsTargeted degradation of MDM2 overcomes feedback regulation of p53 signaling in Merkel cell carcinoma models.
This study explores the efficacy of MDM2 degraders, KTX-049 and KT-253, in treating Merkel cell carcinoma (MCC), an aggressive skin cancer. MCC tumors often exhibit clonal integration of Merkel cell polyomavirus, with virus-positive (MCCP) and virus-negative (MCCN) tumors showing distinct molecular ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-31 | PXD065666 | Pride
ProteomicsHsp90
Hsp90
ORGANISM(S): Homo Sapiens (human) 
2011-12-31 | PAe003656 | PeptideAtlas
UnknownAssessment of antibiotic utilization patterns in an Indian Level-1 Trauma Center: a pilot study exploring days of antibiotic spectrum coverage and defined daily doses using WHO AWaRe classification trends.
Not available
S-EPMC12304517 | biostudies-literature
ProteomicsUltra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling
Regulatory protein phosphorylation controls nearly every normal and pathophysiological signaling system in eukaryotic cells. Despite great advances in mass spectrometry based-proteomics, the total number, localization and site-specific stoichiometry of this post-translational modification (PTM) are ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080701 | MassIVE
ProteomicsCell-type and brain-region resolved mouse brain proteome
To understand the complexity of the brain, connectome and transcriptome maps of high resolution are being generated, but an equivalent catalogue of the brain proteome is lacking. To provide a starting point, we have performed an in-depth proteome analysis of the adult mouse brain, its major regions ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-02-08 | MSV000084941 | MassIVE
Proteomicsyagpm2_2
enrichment for specialized purple membrane proteins, cell culture #2 Goo et al., unpublished data.
ORGANISM(S): Halobacterium Nrc-1 (halobacterium) 
2011-12-31 | PAe000252 | PeptideAtlas
ProteomicsHs_Hela_Tyr_Pervanadate
HeLa S3 cells, Tyr phosphorylation, thymidine block and nocodazole arrest, treated with pervanadate
ORGANISM(S): Homo Sapiens (human) 
2014-12-31 | PAe005300 | PeptideAtlas
ProteomicsHs_Hela_Mitosis
HeLa S3 cells, double thymidine block and nocodazole arrest
ORGANISM(S): Homo Sapiens (human) 
2014-12-31 | PAe005289 | PeptideAtlas
ProteomicsHs_Hela_unstimulated
HeLa S3 cells, untreated control cells
ORGANISM(S): Homo Sapiens (human) 
2014-12-31 | PAe005278 | PeptideAtlas
ProteomicsHs_Hela_Tyr_EGF
HeLa S3 cells, Tyr phosphorylation, double thymidine block and nocodazole arrest, treated with EGF
ORGANISM(S): Homo Sapiens (human) 
2014-12-31 | PAe005240 | PeptideAtlas
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