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GenomicsPromoter proximal pausing and its regulation by c-Myc in embryonic stem cells: ChIP-Seq
Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We describe here evidence that promoter-proximal pausing is a general feature of transcription ...
ORGANISM(S): Mus musculus 
2010-04-02 | E-GEOD-20530 | biostudies-arrayexpress
TranscriptomicsPromoter proximal pausing and its regulation by c-Myc in embryonic stem cells: ChIP-chip
Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We describe here evidence that promoter-proximal pausing is a general feature of transcription ...
ORGANISM(S): Mus musculus 
2010-04-02 | E-GEOD-20529 | biostudies-arrayexpress
TranscriptomicsPromoter proximal pausing and its regulation by c-Myc in embryonic stem cells
This SuperSeries is composed of the following subset Series: GSE20529: Promoter proximal pausing and its regulation by c-Myc in embryonic stem cells: ChIP-chip GSE20530: Promoter proximal pausing and its regulation by c-Myc in embryonic stem cells: ChIP-Seq Refer to individual Series
ORGANISM(S): Mus musculus 
2010-04-14 | E-GEOD-20485 | biostudies-arrayexpress
TranscriptomicsPromoter directionality is controlled by U1 snRNP and polyadenylation signals
Transcription of the mammalian genome is pervasive, but productive transcription outside of protein-coding genes is limited by unknown mechanisms. In particular, although RNA polymerase II (RNAPII) initiates divergently from most active gene promoters, productive elongation occurs primarily in the s...
ORGANISM(S): Mus musculus 
2013-06-28 | E-GEOD-46433 | biostudies-arrayexpress
TranscriptomicsExon array analysis of resting and activated primary murine CD4+ T-cells
The stability, localization and translation of mammalian mRNAs are largely determined by sequences in the 3' untranslated region (UTR). Here, we describe a conserved program of increased upstream polyadenylation site usage following activation of primary murine CD4+ T lymphocytes. This program, re...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-10666 | biostudies-arrayexpress
TranscriptomicsRhodococcus sp. RHA1 grown on propane versus pyruvate
three late exponential phase Rhodococcus sp. RHA1 propane-grown cultures compared to pyruvate-grown cultures three two-colour microarrays
ORGANISM(S): Rhodococcus sp. RHA1 
2010-06-25 | E-GEOD-8480 | biostudies-arrayexpress
UnknownBarium chloride injures myofibers through calcium-induced proteolysis with fragmentation of motor nerves and microvessels.
Not available
S-EPMC6833148 | biostudies-literature
TranscriptomicsGenome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiation [human data]
Endogenous bioelectric signaling via changes in cellular resting potential (Vmem) is a key regulator of patterning during regeneration and embryogenesis in numerous model systems. Depolarization of Vmem has been functionally implicated in de-differentiation, tumorigenesis, anatomical re-specificatio...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-72098 | biostudies-arrayexpress
TranscriptomicsProperties and functions of transcriptionally distinct enteric neurons
In our study, we perform single-cell RNA-seq from various genotypes. These different genotypes allow for isolation of all enteric neurons, excitatory enteric neurons, or inhibitory enteric neurons. We also provide single-cell RNA seq for the celiac-mesenteric ganglia, which is home to sympathetic ...
ORGANISM(S): Mus musculus 
2025-10-31 | E-MTAB-15666 | biostudies-arrayexpress
TranscriptomicsRNA-seq of neuronal SOX2-ablated murine suprachiasmatic nuclei against wild-type littermate controls
Mice lacking the stem/progenitor cell transcription factor, Sex determining region Y-box 2 (SOX2), in neurons of the suprachiasmatic nuclei display imprecise, poorly consolidated behavioral rhythms that do not entrain efficiently to environmental light cycles. RNA sequencing revealed that Sox2 defic...
ORGANISM(S): Mus musculus 
2019-03-18 | E-MTAB-7496 | biostudies-arrayexpress
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