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GenomicsChIP-seq of HNF4A and GATA6 in oesophageal adenocaricnoma OE19 cells
The genome-wide binding sites of transcription factors provide insight into their regulatory function. We used chromatin immunoprecipitaition with high-throughput sequencing (ChIP-seq) to identify the genomic binding sites of HNF4A and GATA6 in OE19 cells.
ORGANISM(S): Homo sapiens 
2019-02-09 | E-MTAB-6858 | biostudies-arrayexpress
TranscriptomicsExpression profiling of exposure to phorbol myristate acetate - PMA and FOXK2 depletion with siRNA
Expression profiling was done of exposure to phorbol myristate acetate -PMA and FOXK2 depletion by siRNA transfection. This was done on the human osteosarcoma U2OS cell line which stably expresses FOXK2. PMA is an inducer of AP1 activity.
ORGANISM(S): Homo sapiens 
2011-11-03 | E-MEXP-3107 | biostudies-arrayexpress
TranscriptomicsExpression profiling of FOXK2 depletion by siRNA
Expression profiling was done of FOXK2 depletion by siRNA transfection. This was done on the human osteosarcoma U2OS cell line (which stably expresses FOXK2).
ORGANISM(S): Homo sapiens 
2011-11-03 | E-MEXP-3106 | biostudies-arrayexpress
TranscriptomicsATAC-seq of oesophageal adenocarcinoma patient samples
Open chromatin profiling (ATAC-seq) of human oesophageal adenocarcinoma patient samples.
ORGANISM(S): Homo sapiens 
2020-09-30 | E-MTAB-8447 | biostudies-arrayexpress
TranscriptomicsATAC-seq of oesophageal cell lines and tissue samples
ATAC-seq in oesophageal cell lines: OE19, HEEPIC, and human eosophageal tissue samples
ORGANISM(S): Homo sapiens 
2017-07-07 | E-MTAB-5169 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human oesophageal adenocarcinoma OE19 cell line treated with lapatinib
To investigate changes to gene expression associated with resistance to lapatinib, we performed ATAC-seq on OE19 cells treated with 500 nM lapatinib for 1, 7 and 35 days and vehicle control (DMSO) for 1 day.
ORGANISM(S): Homo sapiens 
2022-09-26 | E-MTAB-10304 | biostudies-arrayexpress
TranscriptomicsSUMO2 ChIP-seq in MCF10A cells
Chromatin immuno-precipitation using SUMO2 (Life Technologies) antibody in MCF10A cell line, treated with epidermal growth factor for 30 minutes.
ORGANISM(S): Homo sapiens 
2019-07-16 | E-MTAB-7759 | biostudies-arrayexpress
GenomicsGenome-wide mapping of FOXM1 binding sites
There are nearly fifty forkhead (FOX) transcription factors encoded in the human genome and due to sharing a common DNA binding domain, they are all thought to bind to similar DNA sequences. It is therefore unclear how these transcription factors are targeted to specific chromatin regions to elicit ...
ORGANISM(S): Homo sapiens 
2012-11-05 | E-GEOD-38170 | biostudies-arrayexpress
GenomicsETV1 ChIP-seq in OE33 esophageal adenocarcinoma cells
Chromatin immunoprecipitation using anti-ETV1 a.k.a. ER81 (Abcam: ab81086) antibodies or input DNA in an OE33 cell line
ORGANISM(S): Homo sapiens 
2017-07-07 | E-MTAB-5168 | biostudies-arrayexpress
GenomicsKLF5 ChIP-seq in CP-A and OE19 cells
To identify DNA binding sites of KLF5 in CP-A and OE19 cells, we carried out ChIP-seq.
ORGANISM(S): Homo sapiens 
2020-09-30 | E-MTAB-8568 | biostudies-arrayexpress
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